Publications by authors named "Madoka Yamamoto-Sasaki"

Article Synopsis
  • The study examines antipsychotic prescription trends among Japanese children and adolescents (≤17 years) in outpatient settings from 2006 to 2012, using a large dataset.
  • It found that 65.1% of the patients were aged 13-17 and 52.9% were male, with an increase in second-generation antipsychotic monotherapy prescriptions from 53.8% to 78.3% during the study period.
  • Risperidone was the most commonly prescribed drug, and about 25% of patients received initial doses that were lower than recommended.
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Certain studies previously pointed out that treating pregnant women with antidepressants may increase risks of congenital anomalies in their children. However, to date, the study results are not conclusive. Furthermore, most studies have been performed using data from Western countries; therefore, we examined this association using Japanese data.

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Background: Studies using data from Western countries have raised concerns that treating pregnant women with antidepressants may increase the risk of autism spectrum disorders (ASDs) in their offspring. However, to date, the studies are inconclusive. We therefore examined the association between antidepressant use and ASD using claims data collected in Japan.

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