Publications by authors named "Madina P Baranova"

Article Synopsis
  • Ovarian cancer ranks as the fifth most common cause of cancer deaths among women and is the deadliest type of gynecological cancer.
  • The report discusses a unique case of a 26-year-old woman with a recurrent granulosa cell tumor (GCT) in her right ovary that continued to progress despite various treatments.
  • Utilizing a new bioinformatics tool called Oncobox, doctors identified actionable drug options that resulted in a partial response and eventually stabilized her condition over the long term.
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Article Synopsis
  • - Cholangiocarcinoma is a severe cancer with a low survival rate, often diagnosed too late for surgical treatment and usually managed with chemotherapy that only offers about a 12-month median survival.
  • - A case study involving a 72-year-old man with aggressive metastatic cholangiocarcinoma showcases the use of personalized treatment through tyrosine kinase inhibitors (TKIs), starting with sorafenib, which stabilized his condition and improved quality of life for nearly 6 months before switching to Pazopanib.
  • - The study highlights the potential benefits of tailoring TKI therapy based on genetic testing of the tumor, suggesting that personalized treatments can extend survival and enhance the patient's quality of life beyond typical chemotherapy outcomes.
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