Suspecting optic neuritis, diagnosing Bartonella cat scratch disease.

Background: Bartonella cat scratch disease is classically a febrile illness, in conjunction with lymphadenopathy and cat exposure.

Objective: To report 2 atypical cases of cat scratch disease with only blurred vision and headache.

Design: Case reports.

Suppression of human tumor cell proliferation through mitochondrial targeting.

Intracellular calcium signaling plays a central role in cell proliferation. In leukemic cells, the calcium release-activated calcium channels provide a major pathway for calcium entry (I(CRAC)) perpetuating progression through the cell cycle. Although I(CRAC) is under mitochondrial regulation, targeting mitochondrial function has not been exploited to control malignant cell growth.