Publications by authors named "Madiha Habib"

Article Synopsis
  • Intracellular infections like leishmaniasis are hard to treat due to pathogens hiding within host cells and developing drug resistance against existing therapies.* -
  • Melittin, an antimicrobial peptide, shows effectiveness against leishmaniasis but poses risks to host cells due to its toxic effects, limiting its use in treatments.* -
  • A new design strategy creates a therapeutic version of melittin that targets infected cells specifically, improving its effectiveness and safety, and has shown promising results in both cell-based and mouse models.*
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  • Scientists used different doses of ethyl methane sulphonate (EMS) to induce genetic changes in super basmati rice seeds to create diversity.
  • They analyzed 48 mutants using 25 SSR (simple sequence repeat) primers, discovering a high level of genetic variability, with 91 total alleles identified, 82 of which were polymorphic.
  • The study concluded that EMS successfully induced genetic variability, and certain SSR markers could be useful for selecting rice mutants for breeding programs.
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Climate change significantly impacts crop production by inducing several abiotic and biotic stresses. The increasing world population, and their food and industrial demands require focused efforts to improve crop plants to ensure sustainable food production. Among various modern biotechnological tools, microRNAs (miRNAs) are one of the fascinating tools available for crop improvement.

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Breeding crop plants with increased yield potential and improved tolerance to stressful environments is critical for global food security. Drought stress (DS) adversely affects agricultural productivity worldwide and is expected to rise in the coming years. Therefore, it is vital to understand the physiological, biochemical, molecular, and ecological mechanisms associated with DS.

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Climatic variability has been acquiring an extensive consideration due to its widespread ability to impact food production and livelihoods. Climate change has the potential to intersperse global approaches in alleviating hunger and undernutrition. It is hypothesized that climate shifts bring substantial negative impacts on food production systems, thereby intimidating food security.

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Introduction: Iron deficiency affects approximately 30% of the world population and is frequently encountered in hypothyroid patients. Early recognition and prompt treatment of iron deficiency in hypothyroid patients lead to a favorable outcome. The aim of this study is to prove the usefulness of reticulocyte hemoglobin equivalent (Ret-He) as a reliable and effective tool in diagnosis of iron deficiency in hypothyroid patients.

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Plant glutathione peroxidases (GPXs) are the main enzymes in the antioxidant defense system that sustain HO homeostasis and normalize plant reaction to abiotic stress conditions. To understand the major roles of the gene family in rapeseed ( L.), for the first time, a genome-wide study identified 25 genes in the rapeseed genome.

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Article Synopsis
  • Stripe rust, caused by a specific pathogen, significantly reduces wheat yield and quality, making genetic resistance a crucial strategy to combat the disease.
  • Researchers evaluated 465 Pakistani spring wheat genotypes for their responses to stripe rust using 765 single nucleotide polymorphism (SNP) markers across various environments and stages of growth.
  • The study identified twenty SNPs related to seedling stage resistance and thirty SNPs associated with adult plant resistance, providing valuable information for wheat breeders to enhance resistance and yield through marker-assisted selection.
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Cadmium (Cd) is one of the most toxic metals in the environment, and has noxious effects on plant growth and production. Cd-accumulating plants showed reduced growth and productivity. Therefore, remediation of this non-essential and toxic pollutant is a prerequisite.

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Dentine erosion is an increasingly recognised problem, especially in aging population, and various methods have been utilised for its assessment. This narrative review was planned to summarise the methods for the assessment of the early stages of dentine erosion. Relevant original articles published in the English language from 2013 to 2017 were reviewed.

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We conducted the first pilot study to investigate the use of the attenuation coefficient from an optical coherence tomography (OCT) backscattered signal as a measure of surface roughness changes in eroded dentine at an early stage of the erosion process. Ten human premolar root samples were subjected to citric acid treatment before scanning by OCT. The extracted relative attenuation coefficient (μ) from backscattered OCT signals was shown to increase with the duration of acid challenge.

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