Publications by authors named "Madhura Bapte"
Article Synopsis
- The study focuses on the increase in cases of COVID-19 associated mucormycosis (CAM) during the second wave of COVID-19 in India, mainly affecting patients with diabetes.
- Conducted at Noble Hospital in Pune between April 2020 and August 2021, the research involved 59 CAM patients, revealing high mortality rates linked to factors like uncontrolled diabetes and high COVID-19 CT severity scores.
- Treatment success was achieved through surgical debridement and antifungal therapy, with 74.6% of patients recovering, highlighting the urgent need for appropriate steroid use in COVID-19 treatment to prevent complications like CAM.
Background: India, along with the rest of the world, faced the challenging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. The second wave in India lagged behind that in the Western world, due to different timing of seasons. There is scarce data about the differences between the two waves, for intensive care unit (ICU) patients.
View Article and Find Full Text PDFCytokine release syndrome (CRS) or cytokine storm is thought to be the cause of inflammatory lung damage, worsening pneumonia and death in patients with COVID-19. Steroids (Methylprednislone or Dexamethasone) and Tocilizumab (TCZ), an interleukin-6 receptor antagonist, are approved for treatment of CRS in India. The aim of this study was to evaluate the efficacy and safety of combination therapy of TCZ and steroid in COVID-19 associated CRS.
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