Human Pluripotent Stem Cell-Based Assays to Predict Developmental Toxicity.

Human beings are continuously exposed to various toxic substances throughout their lives, which affect their reproductive health and eventually the offspring they give birth to. Mainly, these toxins damage the heart and neurological development of the newborn, but most recently, they have begun to affect the musculoskeletal system as well. These toxins are usually present in food, pharmaceuticals, cosmetics, or even the polluted air that people breathe; as a result, the prevalence of birth defects is steadily rising.

An overview of synthesis, characterization, applications and associated adverse effects of bioactive nanoparticles.

A particle with a diameter ranging from 1 to 100 nm is considered a nanoparticle (NP). Owing to their small size and high surface area, NPs possess unique physical, chemical and biological properties as compared to their bulkier counterparts. This paper describes various physico-chemical as well as green methods that can be used to synthesize different types of NPs including carbon-based, ceramic, metal, semiconductor, polymeric and lipid-based NPs.