Publications by authors named "Madhu S Ratre"

The prevalence of inherited bleeding disorders (BDs) is low in the general population (10-20 per 100,000 individuals), particularly hemophilia B cases, which may remain undiagnosed for a very long time until exposed to some surgical procedure. The dental professional must be aware of the possibility that patients with no previous history of abnormal bleeding may manifest their first bleeding episode in the dental office. Particularly as periodontists, we often encounter patients with bleeding gums and severe bleeding complications may precipitate while performing routine periodontal procedures.

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As implant dentistry expands, the number of implants being placed increases, and so does the prevalence of associated complications, resulting in implant failure if not timely attended. The present case report aims to discuss the successful regenerative management of peri-implantitis by both hard and soft tissue augmentation with a five-year follow-up. A 60-year-old male reported a chief complaint of purulent discharge, 7 mm peri-implant probing depth, and radiographic bone loss with no pathologic mobility of the dental implant.

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COVID-19 pandemic has traumatized deep inside in minds and lives of human beings. Those who have survived are at risk of many post-COVID complications; mucormycosis being one of the most common as well as morbid infections. Mucormycosis is also known as black fungus, it is a life-threatening opportunistic fungal infection.

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Article Synopsis
  • Recent research indicates a link between Vitamin D deficiency and anemia, particularly in patients with periodontitis, who show lower 25(OH) D levels compared to healthy individuals.
  • The study aimed to compare Vitamin D levels and red blood cell indices between patients with generalized Stage III Grade B periodontitis and healthy controls, highlighting the association between these factors.
  • Findings revealed that periodontitis patients had significantly lower levels of 25(OH) D, hemoglobin, and other blood indices, suggesting that managing periodontitis may be important for maintaining adequate Vitamin D levels and preventing anemia.
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Inadequate oral hygiene is the root cause of the initiation and establishment of the periodontal disease. Dental calculus serves as plaque retentive area, thereby contributing to gingivitis and periodontitis. The present unusual case is of a 55-year-old female patient reported to the department of periodontology with a chief complaint of hard deposit at the right maxillary and mandibular posterior region.

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Background: Focal reactive gingival overgrowths (FRGO) are a common observation in a clinical dental practice that may occur in response to external and internal chronic stimuli in form of fibrous connective tissue lesions in the oral mucosa. Gingiva is the most commonly involved site of oral reactive lesions. For the confirmed diagnosis of FRGO not only clinical, but the histopathological presentation of the lesion plays a vital role.

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Background: Plasma cell gingivitis (PCG) is a rare condition of the gingiva, characterized histopathologically by infiltration of plasma cells in connective tissue. Hypersensitivity reaction due to antigen is considered as primary etiological factor.

Case Presentation: The present case is of an 18-year-old male patient suffering from gingival enlargement along with cheilitis.

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Article Synopsis
  • The report discusses a rare case of gingival plasma cell granuloma (PCG) in a 60-year-old hypertensive woman on Amlodipine, highlighting its unique presentation.
  • The importance of thorough investigations is emphasized for accurate diagnosis, especially when considering drug-induced gingival overgrowth as a potential cause.
  • Histopathology analysis confirmed the diagnosis of PCG, differentiating it from other conditions like gingival overgrowth and fibroma.
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Peripheral ossifying fibroma (POF) represents a non-neoplastic, reactive lesion of gingiva. The precise etiopathogenesis of POF is unclear; however, it is suggested to originate from the connective tissue of periodontal ligament. This lesion predominantly occurs in the maxillary anterior region.

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Acute myeloid leukemia (AML) is a malignant neoplasm of myeloid series defined by the presence of immature blast cells (>30%) in peripheral circulation. Oral manifestations are the potential indicators of systemic health and disease. Oral cavity is the frequently and early involved sites in AML.

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Background: Drug-induced gingival overgrowth (DIGO) is a well-known adverse effect of cyclosporine A (CsA) and nifedipine (Nf) therapy. The aim of the present morphometric study was to evaluate the effect of azithromycin (Azi) on the combined GO in rats induced by CsA + Nf combination.

Materials And Methods: Thirty Sprague-Dawley male rats were randomly divided equally into three groups.

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Background: Various studies have shown periodontal disease is one of the risk factors for coronary heart disease (CHD), and periodontal treatment of patients with CHD has also been correlated with reduction in systemic markers of CHD. The aim of this study is to evaluate the effect of non-surgical periodontal treatment (NSPT) on the cardiovascular clinical and biochemical status of patients with CHD.

Methods: Seventy known patients with CHD were allocated randomly to either a control group (C; no periodontal therapy) (n = 35) or an experimental group (E; NSPT in the form of scaling and root planing [SRP]) (n = 35).

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