Publications by authors named "Madhu Nayak"

Objective: To compare the diagnostic efficacy of multiplex polymerase chain reaction (PCR), Mycobacterium leprae-specific repetitive element (RLEP) PCR and loop-mediated isothermal amplification (LAMP) PCR in the diagnosis of pediatric leprosy as an alternative to slit-skin smear (SSS) examination.

Methods: A cross-sectional study was performed on 26 children aged 0-18 years with characteristic skin lesions of leprosy. SSS examination for acid fast bacilli (AFB) was performed for all children.

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Article Synopsis
  • A study was conducted to compare the accuracy of the stool-based CBNAAT test to the gastric aspirate CBNAAT test for diagnosing tuberculosis (TB) in children aged 0-18 years.
  • It involved 100 children and found that the diagnostic accuracy was very similar: 81% for gastric aspirate and 80% for stool samples, with a high agreement rate of 97% between the two methods.
  • The results suggest that stool CBNAAT is a reliable alternative to gastric aspirate CBNAAT for diagnosing TB in children, making the testing process easier and potentially more comfortable for young patients.
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Tardive dysmentia has been described as the behavioral equivalent of tardive dyskinesia in patients with schizophrenia. Its association with tardive dyskinesia and psychopathology has been controversial. The authors assessed 123 inpatients with chronic schizophrenia for presence of tardive dysmentia symptoms/signs.

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