Utility of Tau PET in the diagnostic work up of neurodegenerative dementia among Indian patients.

Background And Objectives: Tau PET is being increasingly appraised as a novel diagnostic modality for dementia work up. Given limited data among South Asians, we assessed the frequency, patterns, phenotypic associations and incremental value of positive Tau PET scans in clinically diagnosed neurodegenerative dementia.

Methods: This cross-sectional study recruited consecutive patients of Alzheimer's disease (AD) and non-AD syndromes (September 2021 to October 2022, India).

14-3-3σ restricts YY1 to the cytoplasm, promoting therapy resistance, and tumor progression in colorectal cancer.

14-3-3σ functions as an oncogene in colorectal cancer and is associated with therapy resistance. However, the mechanisms underlying these observations are not clear. The results in this report demonstrate that loss of 14-3-3σ in colorectal cancer cells leads to a decrease in tumor formation and increased sensitivity to chemotherapy.

Development of a continuous electrochemical reactor incorporated with waste-derived activated carbon electrode for the effective removal of hexavalent chromium from industrial effluent.

Being a recognized carcinogen, hexavalent chromium is hazardous to both human and environmental health. Thus, it is imperative to regulate and oversee their levels in a variety of industries, including textiles, dyes, pigments, and metal finishing. This study strives to reduce Cr(VI) in wastewater by using capacitive deionization in conjunction with an activated carbon-based electrode and a continuous electrochemical reactor (CER).

Molecular characterization of recombinant citrus yellow mosaic badnavirus infecting Coorg mandarin exhibiting yellow mosaic disease symptoms in high humid tropic region of Western Ghats.

Unlabelled: The citrus yellow mosaic badnavirus (CMBV) is one of the most important viruses causing yellowing and declining in different species. The Coorg mandarin, pomelo and grapefruit showing the yellow mosaic disease symptoms were collected from different famers field during the survey. Further viral pathogenicity was confirmed through grafting on Rangpur lime as root stock.

A combined experimental and computational investigation on the OH radical and Cl atom-initiated reaction of 2,3-dichloropropene in troposphere.

Temperature-dependent kinetics of OH radical and Cl atom-initiated reaction of an important halogenated alkene, 2,3-Dichloropropene (23DCP), were investigated using absolute and relative methods over 278-363 K. Pulsed laser photolysis - laser induced fluorescence technique and relative rate method using gas chromatography with flame ionization detector were employed for studying the kinetics of 23DCP with OH radical and Cl atom, respectively. The obtained Arrhenius expressions were k(expt)=(4.

Intelligent diagnostic model for malaria parasite detection and classification using imperative inception-based capsule neural networks.

Malaria is an acute fever sickness caused by the Plasmodium parasite and spread by infected Anopheles female mosquitoes. It causes catastrophic illness if left untreated for an extended period, and delaying exact treatment might result in the development of further complications. The most prevalent method now available for detecting malaria is the microscope.

Non-Bilaterians as Model Systems for Tissue Mechanics.

In animals, epithelial tissues are barriers against the external environment, providing protection against biological, chemical, and physical damage. Depending on the organism's physiology and behavior, these tissues encounter different types of mechanical forces and need to provide a suitable adaptive response to ensure success. Therefore, understanding tissue mechanics in different contexts is an important research area.

First report of causing leaf rust disease on grapevine ( L.) in India.

Grapevine ( L.), a member of the family and native of North America, is grown as a table grape. During the survey for the grapevine diseases in May 2022, we noticed numerous yellow pustules of rust on lower side of leaves of 'Bangalore Bule' in Nandi village (13°22'59.

Tissue and Time Optimization for Real-Time Detection of Apple Mosaic Virus and Apple Necrotic Mosaic Virus Associated with Mosaic Disease of Apple ().

Besides apple mosaic virus (ApMV), apple necrotic mosaic virus (ApNMV) has also been found to be associated with apple mosaic disease. Both viruses are unevenly distributed throughout the plant and their titer decreases variably with high temperatures, hence requiring proper tissue and time for early and real-time detection within plants. The present study was carried out to understand the distribution and titer of ApMV and ApNMV in apple trees from different plant parts (spatial) during different seasons (temporal) for the optimization of tissue and time for their timely detection.

Secured and Privacy-Preserving Multi-Authority Access Control System for Cloud-Based Healthcare Data Sharing.

With continuous advancements in Internet technology and the increased use of cryptographic techniques, the cloud has become the obvious choice for data sharing. Generally, the data are outsourced to cloud storage servers in encrypted form. Access control methods can be used on encrypted outsourced data to facilitate and regulate access.

Identification and multilocus gene characterization of phytoplasmas associated with sweet cherry in India.

Symptoms of leaf roll, swollen nodes, flat branch and witches' broom were observed in five cultivars of sweet cherry from Srinagar, Jammu and Kashmir province, India, during 2019-2021. Phytoplasmas association were confirmed by amplifying 16S rRNAA and Y genes with phytoplasma-specific primers in all symptomatic sweet cherry cultivars in nested PCR assays. Pairwise sequence comparison, phylogeny and virtual RFLP (16S rRNA gene) analyses confirmed the presence of ' Phytoplasma asteris' and ' P.

Exploring flexibility, intermolecular interactions and ADMET profiles of anti-influenza agent isorhapontigenin: A quantum chemical and molecular docking study.

Isorhapontigenin (IRPG) drug emerges as promising efficient inhibitor for H1N1 and H3N2 subtypes which belong to influenza A virus; reported with IC value of 35.62 and 63.50 μM respectively.

Carbon dots decorated cadmium sulphide heterojunction-nanospheres for the enhanced visible light driven photocatalytic dye degradation and hydrogen generation.

Carbon dots (C-dots) developed from beetroot is used for the rational design of cadmium sulphide based heterojunction photocatalysts (C-dots@CdS) using hydrothermal technique. The crystal structure, phase, morphology and optical characteristics of the synthesised materials are determined using X-ray diffraction (XRD), High resolution transmission electron microscopy (HR-TEM), Field emission scanning electron microscopy (FESEM), Energy dispersive X-ray analysis (EDAX), Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy, UV-Visible diffuse reflectance spectroscopy (UV-DRS), photoluminescence spectroscopy (PL spectroscopy), BET adsorption, X-ray photoelectron spectroscopy (XPS) and electrochemical studies. Using C-dots@CdS catalytic system, a superior photocatalytic activity relative to the undecorated CdS is observed.

Development of multiplex RT-PCR assay for simultaneous detection of four viruses infecting apple (Malus domestica).

The major viruses infecting apple cultivars throughout the world including India are apple mosaic virus (ApMV), apple stem pitting virus (ASPV), apple stem grooving virus (ASGV), apple chlorotic leaf spot virus (ACLSV), and recently, a new virus, apple necrotic mosaic virus (ApNMV), was reported from mosaic-infected apple cultivars in India. The aim of this study was to detect the ApNMV virus along with the other three viruses (ApMV, ASPV and ASGV) simultaneously by multiplex RT-PCR. Four primer-pair-produced amplicons of 670, 550, 350 and 210 bp corresponding to ApNMV, ApMV, ASPV and ASGV, respectively, were found to be specific for these viruses when tested individually.

A path model approach to safety compliance and personal factors among electrical workers in India.

This article reports the findings from a safety research survey conducted among the employees of a large public-sector electrical utility in the state of Kerala, India. Responses from 3017 employees were collected by one-to-one interaction using the developed instrument. Personal factors like self-esteem, job stress, personal stress, social support and fatigue of the targeted population were measured.

Tumescent Local Anesthesia in Parotid Abscess - Novel Application of Old Technique.

Tumescent local anesthesia (TLA) is a regional anesthetic technique in which the diluted local anesthetic drug (commonly lidocaine) and epinephrine solution in large volume is injected subcutaneously around the site of incision. The main advantages of TLA are excellent bloodless field and longer duration of analgesia because of addition of epinephrine. Although TLA was used in various surgical procedures, there is no literature to date that has reported its use in the parotid region.

Estimation of structural and mechanical properties of Cadmium Sulfide/PVA nanocomposite films.

Cadmium Sulfide (CdS) nanoparticles have been synthesized by hydrothermal method, and dispersed in varying amounts by weight, in Poly Vinyl Alcohol (PVA) matrix. Subsequently, PVA/CdS nanocomposite films have been characterized and analyzed to estimate CdS nanoparticles effect on the properties of PVA films. Both mechanical and structural properties have been considered for the analysis.

Silicon Carbide-Coated Ceramic Membrane Bioreactor for Sustainable Water Purification.

In the present study, a submerged ceramic membrane bioreactor was used to effectively treat industrial wastewater. The outcome of membrane coatings on the efficacy of the membrane was investigated using a silicon carbide (SiC) coating. The flux data obtained from the study were fitted into two mathematical models, namely, the standard pore blocking model (SPBM) and the complete pore plugging model (CPPM) in order to determine the fouling mechanism.

Application of grey system theory on the influencing parameters of aerobic granulation in SBR.

Aerobic granulation is a promising technology for wastewater treatment. Four operational parameters were selected as influencing factors for this study. Aerobic granulation was experimented with three different values of organic loading rate (3, 6 and 9 kg COD m d), superficial upflow air velocity (SUAV) (2, 3 and 4 cm s), settling time (3, 5 and 10 min) and volume exchange ratio (25%, 50% and 75%) in sequencing batch reactor in nine trials for the optimal performance of aerobic granulation.

Defect induced ferromagnetic interaction in nanostructured nickel oxide with core-shell magnetic structure: the role of Ni(2+) and O(2-) vacancies.

Nanostructured nickel oxide samples with crystallite sizes in the range 32-45 nm are synthesized through a facile chemical route using nickel chloride and ethanol amine as the starting materials. The analysis of the antioxidant activity and DC conductivity of the NiO samples confirmed the presence of both Ni(2+) and O(2-) vacancies. The temperature dependent magnetization studies of the samples are done using a Vibrating Sample Magnetometer in the range 20-300 K.

A comparative study with biologically and chemically synthesized nZVI: applications in Cr (VI) removal and ecotoxicity assessment using indigenous microorganisms from chromium-contaminated site.

In the present communication, we report a comparative study of Cr (VI) removal using biologically synthesized nano zero valent iron (BS-nZVI) and chemically synthesized nZVI (CS-nZVI), both immobilized in calcium alginate beads. The parameters like initial Cr (VI) concentration, nZVI concentration, and the contact time for Cr (VI) removal were optimized based on Box-Behnken design (BBD) by response surface modeling at a constant pH 7. Under the optimized conditions (concentration of nZVI = 1000 mg L(-1), contact time = ∼ 80 min, and initial concentration of Cr (VI) = 10 mg L(-1)), the Cr (VI) removal by the immobilized BS-nZVI and CS-nZVI alginate beads was 80.

Determinants of job stress in chemical process industry: A factor analysis approach.

Background: Job stress is one of the active research domains in industrial safety research. The job stress can result in accidents and health related issues in workers in chemical process industries. Hence it is important to measure the level of job stress in workers so as to mitigate the same to avoid the worker's safety related problems in the industries.