Publications by authors named "Madhan Kumar"

Sodium alginate is a highly promising biopolymer for use as an eco-friendly/green corrosion inhibitor (CI), despite its limited solubility. In this study, a green and water-soluble modified sodium alginate (MSA) salt was synthesized and employed as a CI on pipeline N80 carbon steel (N80CS) in artificial sea water (ASW) medium. Various analytical tools related to surface and structure were utilized to describe the properties of the newly synthesized MSA polymer.

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Introduction:  The Alsin Rho Guanine Nucleotide Exchange Factor ( gene encodes a protein alsin that functions as a guanine nucleotide exchange factor. The variations in gene leads to degeneration of upper motor neurons of the corticospinal tract. The phenotypes resulting from variants in gene are infantile-onset ascending hereditary spastic paralysis (IAHSP, OMIM # 607225), juvenile primary lateral sclerosis (JPLS, OMIM # 606353), and juvenile amyotrophic lateral sclerosis (JALS, OMIM # 205100).

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Oil-mediated nano emulsion, a more advanced technology than other commercial extenders, will protect spermatozoa for extended periods against ROS and cryo injuries. The study is designed to elucidate the most suitable extender to preserve infertile subjects' sperm cells against ROS damage. This is a significant step forward for the andrology society, as it introduces the use of a nano emulsion extender (natural oil extract) for the first time, particularly for those who are undergoing urology-related defects.

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Primary ciliary dyskinesia (PCD) is a rare, motile ciliopathy inherited through mostly autosomal recessive variants that results in chronic ear, sinus, and respiratory disease. Despite neonatal respiratory distress being a common presenting symptom in term infants with PCD, the diagnosis is often delayed due to non-familiarity of neonatal caregivers with phenotypic and diagnostic features of this disease. Organ laterality defects, prenatal cerebral ventriculomegaly, and a family history of suppurative respiratory disease may occur in PCD and should prompt neonatal testing for this condition.

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Medical image denoising has been a subject of extensive research, with various techniques employed to enhance image quality and facilitate more accurate diagnostics. The evolution of denoising methods has highlighted impressive results but struggled to strike equilibrium between noise reduction and edge preservation which limits its applicability in various domains. This paper manifests the novel methodology that integrates an adaptive masking strategy, transformer-based U-Net Prior generator, edge enhancement module, and modified non-local block (MNLB) for denoising brain MRI clinical images.

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Chitosan, as a proficient biopolymer, has enormous potential as an ecofriendly corrosion inhibitor (CI), but their limited solubility restricts practical applications. Herein, an eco-friendly and water-soluble chitosan salt (CS) was utilized as a green CI on N80 pipeline steel in artificial sea water. Several structural and surface analytical tools were engaged in describing the characteristics of novel CS polymer.

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Titanium alloys have gained popularity as a bioimplant material due to their biocompatibility, low modulus of elasticity, and increased strength. However, other issues, such as corrosion resistance, and infections can reduce the implant's lifespan. This paper aims to fabricate a new Ti-30Nb-3Ag at% alloy with enhanced in vitro corrosion and antibacterial properties by mechanical alloying (MA) followed by powder consolidation.

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Prospective Anti-viral compound 3, 5 Dimethyl Pyrazolium 3, 5 Dichloro Salicylate (DPDS) was synthesized and characterized using FT-IR, FT-Raman, UV and NMR spectra. To escort the experimental results, computational methods were performed using B3LYP with 6-311G (d, p) basis set expending Gaussian09w package to attain geometry of the molecule. Vibrational assignments for all the vibrational modes have been made of PED results obtained from SQM method.

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Aim: To study the frequency of iron deficiency anemia (IDA) in individuals with type 2 diabetes mellitus (T2DM) seen at tertiary diabetes care centres across India.

Methods: This is a retrospective study (January 1, 2017-December 31, 2019), which included 1137 individuals with T2DM, aged ≥18 years, for whom data on glycemic, lipid and haematological parameters were available. Anthropometric measurements were done using standardized techniques.

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Background: Most centers in developing countries prefer chelation therapy with D-penicillamine for the management of Wilson's disease (WD) because of its easy availability and affordability. Neurological worsening following treatment with D-penicillamine is not uncommon. However, there is a paucity of Indian data on the incidence of neurological worsening in children and adolescents with WD following chelation therapy.

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Scrub typhus is a zoonotic rickettsial disease caused by the bacterium Orientia tsutsugamushi. The non-specificity of presentation, low index of suspicion and the poor availability of diagnostic tests often lead to delayed diagnosis and significant morbidity and mortality. Temperature, humidity, rainfall and Normalized Difference Vegetation Index (NDVI) on the spatio-temporal clustering of scrub typhus cases in children in three contiguous administrative districts in South India over 5 years were studied.

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Objectives: To describe the demography and spectrum of pancreatic, hepatobiliary, and gastrointestinal (GI) manifestations in children with cystic fibrosis (CF) from the Indian subcontinent.

Methods: In this retrospective study, relevant information from the database of all children with CF below 18 years of age was collected and analyzed.

Results: Among the total 109 children, 58 (53%) were from the southern states of India.

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One of the most challenging and demanding endeavors in the field of prosthodontics is the rehabilitation of an edentulous mandible. Implants have been used to support mandibular or maxillary prosthetic rehabilitation. Advantages of using implants are increased retention, increased chewing ability, and also easy access to oral hygiene procedures.

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Introduction: Extracorporeal membrane oxygenation (ECMO) is increasingly used in managing patients with severe acute respiratory distress syndrome (ARDS). The aim of the study is to describe the practice of ECMO and evaluate the outcomes in patients with severe ARDS in Indian intensive care units (ICUs).

Methods: Data of 39 patients with severe ARDS managed with ECMO in two tertiary centers between 2012 and 2018 were retrospectively studied.

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Polyethyleneimine functionalized graphene oxide (PEI-GO) was prepared and characterized for its molecular structure and morphology. The PEI-GO is, for the first time, reported as an inhibitor against copper (Cu) corrosion in 0.5 M HCl using electrochemical studies.

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A series of UV-protected coatings were prepared using cerium-oxide-functionalized oil fly ash (-OFA-CeO) in waterborne polyurethane (WBPU) dispersions. Three monomers, namely, poly(tetramethyleneoxide glycol) (PTMG), polydimethylsiloxane-hydroxy terminated (PDMS) and 4,4-dicyclohexylmethane diisocyanate (HMDI), were used to pre-mix with -OFA-CeO separately, followed by the synthesis of WBPU/-OFA-CeO dispersions. The -OFA-CeO distribution and enrichment into any part (top/bottom/bulk) of the coating was strongly affected by the pre-mixing of -OFA-CeO.

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