Publications by authors named "Madelynne Olexa"
Article Synopsis
- The study investigated the effects of a tier-based management protocol on brain tissue oxygen levels and intracranial pressure in patients with severe traumatic brain injury, aiming to reduce brain tissue hypoxia.
- A secondary analysis focused on how blood pressure management and interventions to enhance cerebral perfusion pressure could impact brain tissue oxygen levels and overall cerebral health.
- Results from 55 patients showed that interventions to boost cerebral perfusion pressure improved brain oxygen levels, with significant improvements observed following treatment for hypoxia, although autoregulatory function showed only a slight trend towards improvement.
Background And Purpose: Volumetric and densitometric biomarkers have been proposed to better quantify cerebral edema after stroke, but their relative performance has not been rigorously evaluated.
Methods: Patients with large vessel occlusion stroke from three institutions were analyzed. An automated pipeline extracted brain, cerebrospinal fluid (CSF), and infarct volumes from serial CTs.
Our understanding of neuropathic itch is limited due to a lack of relevant animal models. Patients with cutaneous T cell lymphoma (CTCL) experience severe itching. Here, we characterize a mouse model of chronic itch with remarkable lymphoma growth, immune cell accumulation, and persistent pruritus.
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