Publications by authors named "Madeline Tarrillion"

Exposure of the skin to ultraviolet (UV) irradiation causes many detrimental effects through mechanisms related to oxidative stress and DNA damage. Excessive oxidative stress can cause apoptosis and cellular dysfunction of epidermal cells leading to cellular senescence and connective tissue degradation. Direct and indirect damage to DNA predisposes the skin to cancer formation.

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Background: Few reports have described vitiligo developing in patients with cutaneous T-cell lymphoma (CTCL).

Objective: We sought to identify possible factors that might predispose patients with CTCL to vitiligo.

Methods: Patient demographics, CTCL disease characteristics and treatments were analyzed in 25 patients with CTCL who developed vitiligo.

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Synopsis of recent research by authors named "Madeline Tarrillion"

  • - Madeline Tarrillion's research primarily focuses on dermatological effects of environmental factors, specifically the impact of ultraviolet (UV) radiation on skin health and its association with conditions such as skin cancer and other skin disorders.
  • - Her studies highlight the mechanisms of skin damage from UV exposure, detailing oxidative stress and DNA damage as key contributors to cellular dysfunction and aging in epidermal cells.
  • - Tarrillion has also explored the interplay of cutaneous T-cell lymphoma with vitiligo, seeking to understand how this lymphoma may contribute to the destruction of melanocytes in affected patients.