Publications by authors named "Madeline Rapley"
Background: This study investigates a multi-angle acquisition method aimed at improving image quality in organ-targeted PET detectors with planar detector heads. Organ-targeted PET technologies have emerged to address limitations of conventional whole-body PET/CT systems, such as restricted axial field-of-view (AFOV), limited spatial resolution, and high radiation exposure associated with PET procedures. The AFOV in organ-targeted PET can be adjusted to the organ of interest, minimizing unwanted signals from other parts of the body, thus improving signal collection efficiency and reducing the dose of administered radiotracer.
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- The article with DOI: 10.3389/fonc.2024.1405404 has been revised or corrected.
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Article Synopsis
- - Contrast-enhanced breast MRI is recommended for high-risk women but has limitations, such as false positives and increased patient anxiety due to hormonal sensitivity and the potential for overdiagnosis.
- - Breast-targeted PET imaging offers higher specificity and can detect cancers regardless of breast density or hormonal fluctuations, although traditional PET involves high radiation levels, limiting its use in some cases.
- - A case study using the low-dose Radialis PET imager for a 33-year-old patient highlighted its ability to detect lesions with low metabolic activity; however, it did not reveal any malignant areas in this instance, resulting in surgical interventions for tumor removal.
Introduction: A newly developed clinical organ-targeted Positron Emission Tomography (PET) system (also known as Radialis PET) is tested with a set of standardized and custom tests previously used to evaluate the performance of Positron Emission Mammography (PEM) systems.
Methods: Imaging characteristics impacting standardized uptake value (SUV) and detectability of small lesions, namely spatial resolution, linearity, uniformity, and recovery coefficients, are evaluated.
Results: In-plane spatial resolution was measured as 2.