Publications by authors named "Madeline N Fitzpatrick"
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Synopsis of recent research by authors named "Madeline N Fitzpatrick"
Madeline N Fitzpatrick's recent research focuses on the mechanisms underlying lipid metabolism, particularly in relation to macrophage function and lipoprotein interactions.
Her study on THP-1 macrophages highlights the impairment of cholesterol efflux due to palmitoleate and the role of Akt activation in this process, contributing to a better understanding of atherosclerosis progression.
Additionally, she explored the characteristics of a peptide that mimics the heparin binding domain of human hepatic lipase, revealing insights into how this enzyme interacts with cell surfaces and its implications for lipid hydrolysis.