Publications by authors named "Madeleine Warren"

Adults with kidney failure receiving dialysis frequently report high symptom burden that can limit life participation and decrease the quality of life. Fatigue, itch, pain, anxiety, depressive symptoms, sleep problems, nausea, vomiting, muscle cramps, breathlessness, and decreased cognition can negatively impact important daily activities. Nurses are the majority health professional group that provides care for people receiving dialysis and have a major role in managing these symptoms.

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Article Synopsis
  • Low physical activity and functional impairment are common among people on peritoneal dialysis (PD), but exercise can improve their physical and mental health.
  • A survey of 108 PD patients, mainly from Canada and the UK, revealed that most are aware of exercise benefits and 71% engage in physical activity regularly, though there are significant inconsistencies in advice received about safe exercises.
  • Gaps in knowledge among healthcare providers and patients highlight the need for better education and evidence-based guidelines regarding exercise, particularly concerning weightlifting, fluid management, and swimming activities.
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Clotting of the extracorporeal circuit is a complication in the process of hemodialysis that can result in missed or shortened dialysis sessions, higher nursing workload, and elevated cost of treatment. Repercussions of inadequate dialysis may include patient blood loss, fluid overload, build-up of minerals, higher hospitalization rates, and poor quality of life, contributing to increased patient distress. Preventing clotting through anticoagulation therapy is the key to maintaining patency of the dialysis circuit and supporting dialysis adequacy.

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Background: In-centre nocturnal haemodialysis (INHD) offers extended-hours haemodialysis, 6 to 8 h thrice-weekly overnight, with the support of dialysis specialist nurses. There is increasing observational data demonstrating potential benefits of INHD on health-related quality of life (HRQoL). There is a lack of randomised controlled trial (RCT) data to confirm these benefits and assess safety.

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Article Synopsis
  • Low physical activity and poor function are linked to higher risks of complications and mortality in patients on peritoneal dialysis (PD), making exercise crucial for maintaining their independence.
  • A global survey of PD clinicians revealed that a significant majority (94%) support structured exercise programs for PD patients and believe they can safely engage in physical activities.
  • Clinicians from lower middle-income countries are more likely to encourage physical activity compared to those from high-income countries, highlighting the need for better exercise counseling and structured plans in PD care.
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The importance of patient activation (i.e., the knowledge, skills, and confidence one has in managing one's own healthcare) in people with long-term conditions, including kidney disease, is growing.

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Life participation requiring physical activity and physical function is a key patient-reported outcome for people receiving peritoneal dialysis (PD). Clinician guidance is required from multidisciplinary sources regarding exercise and activity advice to address the specific needs of this group. From August 2020 through to June 2021, the Global Renal Exercise Network and the International Society for Peritoneal Dialysis reviewed the published literature and international clinical experience to develop a set of clinical practice points.

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Kidney failure is an important outcome for patients, clinicians, researchers, healthcare systems, payers, and regulators. However, no harmonized international consensus definitions of kidney failure and key surrogates of progression to kidney failure exist specifically for clinical trials. The International Society of Nephrology convened an international multi-stakeholder meeting to develop consensus on this topic.

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The authors investigated the extent to which children's understanding of the distinction between real and apparent emotions varied according to the motivation to hide emotions. Children, aged 6-7 and 10-11 years, were read stories designed to elicit either prosocial or self-protective motivated display rules and were asked to predict the facial expressions the protagonists would make to hide felt emotions. Children were found to understand the distinction between real and apparent emotions very well, independently of the type of motivation.

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