CoQ and Cognition a Review and Study Protocol for a 90-Day Randomized Controlled Trial Investigating the Cognitive Effects of Ubiquinol in the Healthy Elderly.

: With an aging population there is an important need for the development of effective treatments for the amelioration of cognitive decline. Multiple mechanisms underlie age-related cognitive decline including cerebrovascular disease, oxidative stress, reduced antioxidant capacity and mitochondrial dysfunction. CoQ is a novel treatment which has the potential to improve brain function in healthy elderly populations due to established beneficial effects on mitochondrial function, vascular function and oxidative stress.

Working memory load affects early affective responses to concrete and abstract words differently: Evidence from ERPs.

Early posterior negativity (EPN) is an early-occurring, event-related, potential that is elicited by pictures and words that have highly arousing characteristics. Whilst EPN has been found with words presented in isolation several times, different types of words have shown quite different effects across different types of tasks. One possible reason for this is that memory and attentional demands may affect the way semantic features of words are processed, and this may modulate EPN.