Publications by authors named "Madeleine Ing"
Article Synopsis
- Hospitalized infants often receive opioids to manage pain during procedures, but prolonged use can adversely affect their neurodevelopment.
- A systematic review revealed 14 studies addressing opioid dosing conversions for infants under 1 year, but the conversion factors were inconsistent and mainly based on adult data.
- To improve opioid management for these infants, there is a need for a standardized, evidence-based approach that considers their unique physiological needs.
Article Synopsis
- High-risk infants hospitalized in the U.S. face extremely high healthcare costs, especially those exposed to opioids, which are not fully understood.
- Researchers analyzed data from 126,897 high-risk infants admitted to children's hospitals between 2010 and 2020, focusing on factors like opioid usage and its financial impact on hospitalization costs.
- Findings indicate that each day of opioid use increases healthcare costs significantly, emphasizing the need for future research on the long-term implications and expenses related to opioid exposure in these vulnerable infants.
Importance: High-risk infants, defined as newborns with substantial neonatal-perinatal morbidities, often undergo multiple procedures and require prolonged intubation, resulting in extended opioid exposure that is associated with poor outcomes. Understanding variation in opioid prescribing can inform quality improvement and best-practice initiatives.
Objective: To examine regional and institutional variation in opioid prescribing, including short- and long-acting agents, in high-risk hospitalized infants.
Background: Historically, cholecystectomy is infrequently performed in children. Lifestyle changes, delays in healthcare access, and increases in childhood obesity occurred during the COVID-2019 pandemic. It is unclear whether these changes impacted pediatric gallbladder disease and the need for cholecystectomy.
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