Publications by authors named "Madeleine Aby Diallo"
Nature and evolution of the cellular HIV-1 reservoir in children and adolescents.
Virologie (Montrouge)
October 2023
Article Synopsis
- HIV hides in cellular reservoirs after initial infection, making it hard to eliminate without effective therapy, leading to a decline in immune cells and disease progression.
- The progression of HIV in children differs from adults, with higher viral loads and greater challenges in sticking to treatment, resulting in a shorter life expectancy without intervention.
- There is limited understanding of the cellular reservoirs in children and their impact on HIV progression, but some instances of spontaneous remission in children raise hopes for potential cures for both kids and adults.
[Nature and evolution of the cellular HIV-1 reservoir in children and adolescents].
Virologie (Montrouge)
October 2023
Article Synopsis
- HIV hides in cellular reservoirs after primary infection, making it difficult to eliminate and often leading to disease progression without antiretroviral therapy.
- Children with perinatal HIV infection face different challenges than adults, such as higher viral loads and greater difficulties in maintaining treatment adherence, resulting in shorter life expectancy without treatment.
- There is limited understanding of the cellular reservoirs in children with HIV, but some cases of spontaneous remission have raised hopes for potential cures for both adults and children.