Publications by authors named "Madeiha Qasmieh"
Article Synopsis
- The study developed a new dexamethasone mixed micellar system (DEX-MM) using Soluplus and Pluronic F-127 to improve drug delivery to the eyes by creating a chitosan-coated version (DEX-CMM).
- The DEX-CMM exhibited high stability, uniform particle size, and effective prolonged drug release compared to a standard DEX suspension, enhancing drug absorption and permeation in ocular tissues.
- Safety tests indicated that DEX-CMM is non-irritating, supporting its potential as an effective method for delivering medication to the eyes.
Recent Advances in Ocular Drug Delivery: Insights into Lyotropic Liquid Crystals.
Pharmaceuticals (Basel)
October 2024
This review examines the evolution of lyotropic liquid crystals (LLCs) in ocular drug delivery, focusing on their ability to address the challenges associated with traditional ophthalmic formulations. This study aims to underscore the enhanced bioavailability, prolonged retention, and controlled release properties of LLCs that significantly improve therapeutic outcomes. This review synthesizes data from various studies on both bulk-forming LLCs and liquid crystal nanoparticles (LCNPs).
View Article and Find Full Text PDF