Early Squamous Cell Carcinoma With Perineural Invasion: A Prospective Study Examining Anatomic Site, Tumor Surface Diameter, Invasion Depth, and Grade of Differentiation in 1,772 Consecutive Cases.

Background: Squamous cell carcinoma (SCC) may present with perineural invasion (PNI).

Objective: To investigate the characteristics of early invasive SCC with or without PNI.

Methods: Consecutive SCC excisions were prospectively reviewed from a single Australian community-based practice for 2016-2018.