Publications by authors named "Madalina Szep"
There are different breast cancer molecular subtypes with differences in incidence, treatment response and outcome. They are roughly divided into estrogen and progesterone receptor (ER and PR) negative and positive cancers. In this retrospective study, we included 185 patients augmented with 25 SMOTE patients and divided them into two groups: the training group consisted of 150 patients and the validation cohort consisted of 60 patients.
View Article and Find Full Text PDFArticle Synopsis
- Breast cancer is categorized into five molecular subtypes, each with distinct incidence, survival rates, and treatment responses, and multiparametric MRI is useful for evaluating these tumours in a preoperative context.
- This retrospective study examined the MRI features of 344 patients with various breast cancer subtypes, analyzing aspects like T2-weighted images, ADC values, and dynamic contrast-enhanced imaging.
- Results indicated specific associations between MRI characteristics and each subtype, with ADC values showing potential in predicting luminal B HER2 negative tumours.*
The purpose of this study is to evaluate the relationship between the pathogenic/likely pathogenic mutations, US features, and histopathologic findings of breast cancer in mutation carriers compared to non-carrier patients. Methods: In this retrospective study, we identified 264 patients with breast cancer and multigene panel testing admitted to our clinic from January 2018 to December 2020. Patient data US findings, US assessment of the axilla, multigene panel tests, histopathology, and immunochemistry reports were reviewed according to the BI-RADS lexicon.
View Article and Find Full Text PDFThe aim of this study is to evaluate the role of US in depicting axillary nodal disease in high-risk patients with and without pathogenic mutations. The retrospective study included consecutive high-risk breast cancer (BC) patients who underwent a multigene testing panel for hereditary cancers, pre-operative axillary US and breast/axillary surgery. The group was divided into patients with pathogenic mutations (PM group) and patients without PM.
View Article and Find Full Text PDFArticle Synopsis
- * It aids in identifying and characterizing nipple lesions, making it a preferred choice for initial assessment.
- * The study also correlates outcomes from mammography and MRI with histopathological findings in relevant cases.
Shear wave elastography (SWE) is the newer of the two methods of measuring tissue stiffness using ultrasound. We present the case of a 39-year-old patient with fibrocystic breast disease who presented with a left painful breast lump. The patient underwent a breast ultrasound that depicted a complicated cyst with a "pseudo-solid" content.
View Article and Find Full Text PDFAims: The purpose of this study was to determine the impact of strain elastography (SE) on the Breast Imaging Reporting Data System (BI-RADS) classification depending on invasive lobular carcinoma (ILC) lesion size.
Materials And Methods: We performed a retrospective analysis on a sample of 152 female subjects examined between January 2010 - January 2017. SE was performed on all patients and ILC was subsequently diagnosed by surgical or ultrasound-guided biopsy.