Lactic Acid Bacteria Isolates and the Microbiome of Cincalok, Tempoyak, and Mandai: A Traditional Fermented Food from Kalimantan Island, Indonesia.

Indonesia has abundant traditional fermented food with various lactic acid bacteria (LAB), which can be developed into probiotics for pharmaceutical and functional food and feed products. This research is aimed at (1) obtaining and identifying LAB isolates and (2) studying the microbiome (bacterial diversity and abundance) of spontaneously-fermented traditional foods of Kalimantan Island, Cincalok, Tempoyak, and Mandai. To obtain LAB isolates, food samples were serially diluted and inoculated on MRS agar that contained 1% CaCO (MRSA).

Marine Ascomycetes Extract Antifungal Susceptibility against Candida spp. Isolates from Oral Candidiasis HIV/AIDS Patient: An In Vitro Study.

Objective:  The etiology of oral candidiasis (OC) was , , , that are frequently found in human immunodeficiency virus/ acquired immunodeficiency syndrome (HIV/AIDS) patients. Marine ascomycetes (MA) have been widely reported as an important producer of various antibiotic compounds. However, there is limited study of antifungal compounds from MA against species.

Protaetiibacter mangrovi sp. nov., isolated from mangrove soil.

A novel Gram-stain-positive, aerobic, non-flagellated and rod-shaped actinobacterium, designated 10F1B-8-1, was isolated from mangrove soil sampled at Futian Mangrove Nature Reserve, China. The isolate was able to grow at 10-40 °C (optimum 30-32 °C), at pH 6-8 (optimum 7) and in the presence of 0-6% (w/v) NaCl (optimum 0%). Strain 10F1B-8-1 shared the highest 16S rRNA gene sequence similarity to Protaetiibacter larvae NBRC 113051 (98.

Overview of microplastics in the environment: type, source, potential effects and removal strategies.

The introduction of plastic sectors has resulted in the presence of microplastics (MPs) in water systems, which has become a global issue that has attracted scientific and community awareness. MPs can be detected in a variety of sources such as beauty products, manufacturing effluent, or fishing activities. This study examined the repercussions posed by MPs' prevalence on land and marine environments and human health issues.

Anti-Periodontopathogenic Ability of Mangrove Leaves (Aegiceras corniculatum) Ethanol Extract: In silico and in vitro study.

Objective:  Mangrove () is an abundant natural marine resource of Indonesia, which can be explored for treating periodontal disease due to its potential as immunoregulatory, antibacterial, and antioxidant properties. The objective of this study was to investigate the active compound from Indonesian mangrove leaf extract () (MLE) for developing a herbal-based mouthwash through and studies.

Materials And Methods:  Phytochemistry and liquid chromatography-high resolution mass spectrometry (LC-HRMS) were done to explore the active compounds in MLE.

Isolation and enzyme bioprospection of bacteria associated to , a mangrove plant of North Sumatra, Indonesia.

Mangrove-associated bacteria are of industrial interest due to their diverse and versatile enzyme properties. This study investigates the culturable bacteria from a wide range of habitat in a mangrove ecosystem in North Sumatra. Screening of extracellular hydrolytic enzymes showed multiple potential traits in amylase, cellulase, chitinase, phosphatase, protease, and urease production by bacterial isolates.

TMKS8A, an antibacterial and cytotoxic chlorinated α-lapachone, from a sea slug-derived actinomycete of the genus Streptomyces.

TMKS8A (1), a new chlorinated α-lapachone derivative, along with five known related metabolites, A80915 C (2), SF2415B1 (3), chlorinated dihydroquinone 3 (4), SF2415B3 (5), and A80915 C (6), were identified from the culture extract of Streptomyces sp. TMKS8, which was isolated from a sea slug, Paromoionchis tumidus. The structure of 1 was determined by the analysis of NMR and MS spectral data, assisted by NMR chemical shift prediction using DFT-based calculation.

Nocarimidazoles C and D, antimicrobial alkanoylimidazoles from a coral-derived actinomycete sp.: application of coupling constants for the unequivocal determination of substituted imidazoles and stereochemical diversity of anteisoalkyl chains in microbial metabolites.

Chemical investigation of secondary metabolites from a marine-derived actinomycete strain of the genus , isolated from a stony coral sp., led to the identification of two new alkanoylimidazoles, nocarimidazoles C () and D () as well as three known congeners, nocarimidazoles A () and B () and bulbimidazole A (). Structure analysis of and by NMR and MS revealed that both are 4-alkanoyl-5-aminoimidazoles with a 6-methyloctanoyl or decanoyl chain, respectively.

A New Citrinin Derivative from the Indonesian Marine Sponge-Associated Fungus .

Sponge-associated fungi are attractive targets for the isolation of bioactive natural products with different pharmaceutical purposes. In this investigation, 20 fungi were isolated from 10 different sponge specimens. One isolate, the fungus strain WK-P9, showed activity against JH642 when cultivated in malt extract medium.

Two new aromatic polyketides from a sponge-derived .

In our natural product screening program from marine fungi, two new aromatic polyketides karimunones A () and B () and five known compounds (-) were isolated from sponge-associated sp. KJMT.FP.