Subcutaneous hydromorphone hydrochloride provides antinociception with transient adverse effects in four-toed hedgehogs (Atelerix albiventris).

Objective: To evaluate the efficacy and safety of hydromorphone administered SC in four-toed hedgehogs (Atelerix albiventris).

Animals: 12 healthy adult hedgehogs.

Methods: Hedgehogs underwent 2 randomized, blinded, placebo-controlled, complete crossover studies.

Efficacy and safety of subcutaneous methadone hydrochloride in four-toed hedgehogs (Atelerix albiventris).

Objective: To evaluate the efficacy and safety of SC methadone in four-toed hedgehogs.

Animals: 9 to 12 healthy adult four-toed hedgehogs (7 to 9 males and 3 females).

Methods: Hedgehogs underwent 3 randomized, blinded, placebo-controlled, complete crossover studies.