- Calves are very vulnerable to gastrointestinal infections, especially from pathogens like C. parvum, which can lead to severe diarrhea, poor growth, or even death. Consequently, studying the interaction between the pathogen and the gut microbiota is essential for developing better treatment strategies.
- In a study with neonatal calves challenged by C. parvum, significant symptoms like fever and diarrhea were observed five days after exposure, along with signs of severe intestinal inflammation and an unbalanced gut microbiome characterized by harmful bacteria and toxins.
- Supplementing calves with high-quality colostrum showed some promise in easing clinical symptoms and improving gut immune responses, making the gut environment resemble that of healthy calves, although its overall effectiveness in reducing diarrhea was limited.