Publications by authors named "Mackeler-Ramos Polassi"
Background: Oral care products containing bioactive agents obtained from extracts of plant drugs were launched. This study investigated the effects of herbal-containing toothpastes associated or not with fluoride to remineralize the enamel after cariogenic challenge with pH cycling. The chemical and physical factors of toothpastes and the enamel surface roughness after brushing were also analyzed.
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- * Bovine incisors were treated with different tannin-containing extracts, but overall, the bond strength of the restoratives to dentin did not significantly improve, except for one extract (TNA) that performed differently.
- * While some extracts impacted the contact angle beneficially, indicating potentially better adhesive penetration, they generally weakened the dentin's elastic properties and raised concerns about their effectiveness in prolonging the durability of bonded dental repairs.
Objectives: This study evaluated the cell viability and expression of different major genes involved in mineralization in odontoblast-like cells exposed to sodium trimetaphosphate (STMP). It was also investigated the influence of STMP on the rate of calcium phosphate crystal growth, its anti-proteolytic action against the enzymatic degradation of type I collagen, the binding mechanism of STMP to collagen fibrils, and the potential mechanism to induce collagen stabilization.
Methods: Immortalized rat odontoblast MDPC-23 cells were cultured.
Effects of 1450-ppm Fluoride-containing Toothpastes Associated with Boosters on the Enamel Remineralization and Surface Roughness after Cariogenic Challenge.
Eur J Dent
February 2020
Objectives: This study investigated the remineralization potential of 1450 ppm, fluoride-containing toothpastes containing different active remineralization agents after cariogenic challenge with pH cycling. The enamel surface roughness after brushing and the chemical and physical characteristics of the toothpastes tested were also analyzed.
Materials And Methods: Fifty-six bovine enamel blocks were obtained (4 × 4 × 6 mm) and divided into three thirds: intact (untreated), demineralized (artificial caries lesion), and treated (caries lesion, pH cycling, and brushing with dentifrices).
Influence of a propolis-based irrigant solution on gap formation and bond strength of posts bonded to root canal dentin using different resin cements.
Dent Mater J
June 2020
Article Synopsis
- * Five distinct irrigation protocols were tested, and various cement types were used to bond posts in endodontically-treated bovine incisors.
- * The results showed that RelyX U200 provided better gap-free interfaces, and using PROP did not negatively impact bond strength or surface roughness compared to traditional irrigation methods.
Oxidative stress induced by self-adhesive resin cements affects gene expression, cellular proliferation and mineralization potential of the MDPC-23 odontoblast-like cells.
Dent Mater
April 2019
Objective: Clinical issues have been raised about problems related to cytotoxic effects caused when applying self-adhesive cement. It was hypothesized that byproducts eluted from self-adhesive cements modulate oxidative stress response, the gene expression of signaling pathways of inflammatory process/transcriptional activators, and the expression and activity of interstitial collagenases, and modify the phenotypic characteristics of cellular proliferation and mineral deposition in odontoblastic-like cells.
Methods: Cements (MaxCem Elite [MAX] and RelyX U200 [U200)]) were mixed, dispensed into moulds, and photoactivated according to the manufacturers' instructions.