Publications by authors named "Maciej T Paluch"
Innovative protein engineering and chemical conjugation technologies have yielded an impressive number of drug candidates in clinical development including >80 antibody drug conjugates, >60 bispecific antibodies, >35 Fc-fusion proteins and >10 immuno-cytokines. Despite these innovations, technological advances are needed to address unmet medical needs with new pharmacological mechanisms. Age-related eye diseases are among the most common causes of blindness and poor vision in the world.
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- This text provides a correction to the original article associated with DOI: 10.1038/ncomms11473.
- It addresses specific errors or inaccuracies that were identified in the initial publication.
- The correction ensures that readers have access to the most accurate and reliable information regarding the research findings.
Article Synopsis
- Viruses have proteins that help them dodge the host's immune system, but there hasn't been a comprehensive study on how they interact outside of cells.
- Researchers used E3 proteins from human adenoviruses to explore these interactions, revealing 51 new virus-host connections through a large-scale protein interaction screen.
- The study highlights common and diverse strategies used by viruses to manipulate immune responses, discovering significant interactions with immune receptor families that suggest unknown mechanisms of immune regulation.