Experimental evidence and physiological significance of the ascorbate passive diffusion through the lipid bilayer.

The diverse range of functions performed by ascorbate in many metabolic processes requires its effective redistribution between various aqueous body compartments. It is believed that this hydrophilic molecule needs protein transporters for crossing the biological membrane barriers. Any effective model reflecting the ascorbate distribution within the body requires bi-directional fluxes, but only the ascorbate transporters facilitating its intake by cells have been identified to date.

New oral liposomal vitamin C formulation: properties and bioavailability.

Vitamin C is the exogenous compound necessary for a variety of metabolic processes; therefore, the efficient delivery is critical for the maintenance of body homeostasis. Vitamin C pharmacokinetics and low quantities in processed foodstuff, necessitates its continuous supplementation. In the paper, we present the new liposomal formulation of vitamin C free of harmful organic solvents.

Effect of monovalent anions on water transmembrane transport.

Biological structures consist of lipid bilayers immersed in the aqueous phase. They can be considered as a two-phase system where the two phases are separated (connected) by the transition regions (interphases), which properties are affected by both lipid and aqueous phases. Interphase structure and dynamics might influence properties and/or functioning of the lipid bilayer core, including osmotically induced water flow.