Review of sample-based methods used in an analysis of multistable dynamical systems.

Sample-based methods are a useful tool in analyzing the global behavior of multi-stable systems originating from various branches of science. Classical methods, such as bifurcation diagrams, Lyapunov exponents, and basins of attraction, often fail to analyze complex systems with many coexisting attractors. Thus, we have to apply a different strategy to understand the dynamics of such systems.

The role of TNF-α inhibitor in glioma virotherapy: A mathematical model.

Virotherapy, using herpes simplex virus, represents a promising therapy of glioma. But the innate immune response, which includes TNF-α produced by macrophages, reduces the effectiveness of the treatment. Hence treatment with TNF-α inhibitor may increase the effectiveness of the virotherapy.