The Role of Complete Blood Count-Derived Inflammatory Biomarkers as Predictors of Infection After Acute Ischemic Stroke: A Single-Center Retrospective Study.

: Although a wide range of hematological parameters are used as blood-based inflammatory biomarkers, the role of complete blood count-derived inflammatory biomarkers in infection after acute ischemic stroke (AIS) is modest. Therefore, this study aimed to explore complete blood count-derived inflammatory biomarkers as predictors of infection after AIS. : A single-center retrospective cross-sectional study was carried out at the National Brain Center Hospital Prof.

Hydrogen Production and Li-Ion Battery Performance with MoS-SiNWs-SWNTs@ZnONPs Nanocomposites.

This study explores the hydrogen generation potential via water-splitting reactions under UV-vis radiation by using a synergistic assembly of ZnO nanoparticles integrated with MoS, single-walled carbon nanotubes (SWNTs), and crystalline silicon nanowires (SiNWs) to create the MoS-SiNWs-SWNTs@ZnONPs nanocomposites. A comparative analysis of MoS synthesized through chemical and physical exfoliation methods revealed that the chemically exfoliated MoS exhibited superior performance, thereby being selected for all subsequent measurements. The nanostructured materials demonstrated exceptional surface characteristics, with specific surface areas exceeding 300 m g.

A Single-Center Retrospective Study of Bacterial Infections After Acute Ischemic Stroke: The Prevalence Before and During the COVID-19 Pandemic.

: The management of ischemic stroke involves care that is integrated and comprehensive, including the prevention of infection complications. This study aimed to investigate the prevalence and profile of bacterial infections after acute ischemic stroke both before and during the coronavirus disease 2019 (COVID-19) pandemic. : A retrospective cross-sectional study examined the medical records of hospitalized acute ischemic stroke patients who had microbiological cultures taken at the National Brain Center Hospital Prof.

Neoadjuvant Radiotherapy and Endocrine Therapy for Oestrogen Receptor Positive Breast Cancers: The Neo-RT Feasibility Study.

Aims: To establish the safety and feasibility of delivering neoadjuvant radiotherapy and endocrine therapy for oestrogen receptor-positive breast cancers with palpable size 20mm or greater, for which radiotherapy might facilitate more conservative surgery.

Materials And Methods: A single-arm feasibility study was conducted. Patients received whole breast radiotherapy with or without radiotherapy to nodal areas.

Quality and impact of pharmacology digital simulation education on pre-registration healthcare students: A systematic literature review.

Objective: This review aimed to assess the quality and nature of the literature related to digital simulation-based pharmacology education. Specifically, we sought to understand the influence of simulations on the knowledge, satisfaction, and confidence of pre-registration nurses and other healthcare students participating in such educational programs.

Design: Systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Statement.

Calculating daily dose in the Observational Medical Outcomes Partnership Common Data Model.

Purpose: We aimed to develop a standardized method to calculate daily dose (i.e., the amount of drug a patient was exposed to per day) of any drug on a global scale using only drug information of typical observational data in the Observational Medical Outcomes Partnership Common Data Model (OMOP CDM) and a single reference table from Observational Health Data Sciences And Informatics (OHDSI).

Advancements in Photovoltaic Cell Materials: Silicon, Organic, and Perovskite Solar Cells.

The evolution of photovoltaic cells is intrinsically linked to advancements in the materials from which they are fabricated. This review paper provides an in-depth analysis of the latest developments in silicon-based, organic, and perovskite solar cells, which are at the forefront of photovoltaic research. We scrutinize the unique characteristics, advantages, and limitations of each material class, emphasizing their contributions to efficiency, stability, and commercial viability.

Synergistic Effects of CoO-gCN-Coated ZnO Nanoparticles: A Novel Approach for Enhanced Photocatalytic Degradation of Ciprofloxacin and Hydrogen Evolution via Water Splitting.

This research evaluates the efficacy of catalysts based on CoO-gCN@ZnONPs in the degradation of ciprofloxacin (CFX) and the photocatalytic production of H through water splitting. The results show that CFX experiences prompt photodegradation, with rates reaching up to 99% within 60 min. Notably, the 5% (CoO-gCN)@ZnONPs emerged as the most potent catalyst.

The influence of practice experiences on feelings of role proficiency in emergency nurse practitioners: A phenomenological study.

Introduction: This research explores how emergency nurse practitioners (ENPs) become role proficient given experience variation and lack of role standardisation.

Aim: To understand how ENPs experiences in practice influence their feelings of role proficiency.

Methods: A hermeneutic phenomenological study was undertaken utilizing an interpretive standpoint.

Artificial Photosynthesis: Current Advancements and Future Prospects.

Artificial photosynthesis is a technology with immense potential that aims to emulate the natural photosynthetic process. The process of natural photosynthesis involves the conversion of solar energy into chemical energy, which is stored in organic compounds. Catalysis is an essential aspect of artificial photosynthesis, as it facilitates the reactions that convert solar energy into chemical energy.

Democracy, Agony, and Rupture: A Critique of Climate Citizens' Assemblies.

Stymied by preoccupation with short-term interests of individualist consumers, democratic institutions seem unable to generate sustained political commitment for tackling climate change. The citizens' assembly (CA) is promoted as an important tool in combatting this "democratic myopia." The aim of a CA is to bring together a representative group of citizens and experts from diverse backgrounds to exchange their different insights and perspectives on a complex issue.

Educators' perceptions of their experiences of transnational education in nursing: A grounded theory study.

Aim: The study aim was to explore educators' perceptions of their experiences of participating in transnational education in nursing.

Background: In an increasingly globalised world, involvement with the delivery of transnational education has become commonplace across the international higher education sector. In recent years, transnational education within the academic discipline of nursing has developed at pace, evolving in response to a global need to invest in nurse education, address nursing shortages and strengthen nursing leadership.

Biomimetic Catalysts Based on Au@TiO-MoS-CeO Composites for the Production of Hydrogen by Water Splitting.

The photocatalytic hydrogen evolution reaction (HER) by water splitting has been studied, using catalysts based on crystalline TiO nanowires (TiONWs), which were synthesized by a hydrothermal procedure. This nanomaterial was subsequently modified by incorporating different loadings (1%, 3% and 5%) of gold nanoparticles (AuNPs) on the surface, previously exfoliated MoS nanosheets, and CeO nanoparticles (CeONPs). These nanomaterials, as well as the different synthesized catalysts, were characterized by electron microscopy (HR-SEM and HR-TEM), XPS, XRD, Raman, Reflectance and BET surface area.

Understanding Patients with COVID in the Isolation Rooms from the Perspective of Care: A Qualitative Study.

Introduction: Being treated in isolation rooms for people infected with COVID-19, creates various perceptions of uncertainty, especially when strict "health protocols" are applied. This study aims to determine the understanding patients with COVID in the intensive care unit from the perspective of care.

Materials And Methods: The research design used phenomenological qualitative with in-depth interviews.

The Effect of Green Tea with EGCG Active Compound in Enhancing the Expression of M2 Microglia Marker (CD206).

Background: Stroke is a neurological deficit due to vascular disorders. Microglia are the first line of defense against brain injury. Anti-inflammatory cytokines activate M2 microglia, which upregulate CD206.

Multiparametric MRI for assessment of early response to neoadjuvant sunitinib in renal cell carcinoma.

Purpose: To detect early response to sunitinib treatment in metastatic clear cell renal cancer (mRCC) using multiparametric MRI.

Method: Participants with mRCC undergoing pre-surgical sunitinib therapy in the prospective NeoSun clinical trial (EudraCtNo: 2005-004502-82) were imaged before starting treatment, and after 12 days of sunitinib therapy using morphological MRI sequences, advanced diffusion-weighted imaging, measurements of R2* (related to hypoxia) and dynamic contrast-enhanced imaging. Following nephrectomy, participants continued treatment and were followed-up with contrast-enhanced CT.

Dynamic biomarker and imaging changes from a phase II study of pre- and post-surgical sunitinib.

Objective: To explore translational biological and imaging biomarkers for sunitinib treatment before and after debulking nephrectomy in the NeoSun (European Union Drug Regulating Authorities Clinical Trials Database [EudraCT] number: 2005-004502-82) single-centre, single-arm, single-agent, Phase II trial.

Patients And Methods: Treatment-naïve patients with metastatic renal cell carcinoma (mRCC) received 50 mg once daily sunitinib for 12 days pre-surgically, then post-surgery on 4 week-on, 2 week-off, repeating 6-week cycles until disease progression in a single arm phase II trial. Structural and dynamic contrast-enhanced magnet resonance imaging (DCE-MRI) and research blood sampling were performed at baseline and after 12 days.

Green tea and its active compound epigallocathechin-3-gallate (EGCG) inhibit neuronal apoptosis in a middle cerebral artery occlusion (MCAO) model.

Objectives: To determine the effect of green tea with the active ingredient epigallocathechin-3-gallate (EGCG) on the inhibition of apoptosis in the middle cerebral artery occlusion (MCAO) model.

Methods: Four month old male rats with a body weight of 200-275 g was used for the MCAO model and divided into five groups, and the treatment was carried out for 7 days. Before being sacrificed, the subject had 1 cc of blood drawn for high mobility group box 1 (HMGB-1) examination using enzyme-linked immunosorbent assay (ELISA), and after being sacrificed, the brain tissue specimen was taken to examine caspase-3 and B-cell lymphoma 3 (BCL-3) using immunohistochemistry methods.

The effect of (green tea) with its active compound EGCG on neuronal cell necroptosis in middle cerebral artery occlusion (MCAO) model.

Objectives: To determine the inhibition effect of (EGCG) and green tea extract on neuronal necroptosis based on necroptosis morphology.

Methods: study was performed on male middle cerebral artery occlusion (MCAO) model divided into five groups, MCAO-control groups, EGCG 10 mg/kg BW/day, EGCG 20 mg/kg BW/day, EGCG 30 mg/kg BW/day, and green tea extract 30 mg/kg BW/day for 7 days treatment. MCAO model was made by modification method using Bulldog clamp.

Compassion in nursing: exploring the perceptions of students and academics.

Background: Compassion is integral to effective nursing practice, yet there is limited empirical research exploring this concept, particularly from a professional perspective. Aim To advance understanding of compassion from a professional perspective, specifically through the perceptions of students and academics from the fields of adult, child, learning disability and mental health nursing.

Method: A constructivist grounded theory study was undertaken, and a theoretical sampling strategy was used to guide the selection of appropriate participants.

One-Dimensional (1D) Nanostructured Materials for Energy Applications.

At present, the world is at the peak of production of traditional fossil fuels. Much of the resources that humanity has been consuming (oil, coal, and natural gas) are coming to an end. The human being faces a future that must necessarily go through a paradigm shift, which includes a progressive movement towards increasingly less polluting and energetically viable resources.