Publications by authors named "Machi Hosaka"

Substances released outside of the cells during cell necrosis are collectively called danger-associated molecular patterns (DAMPS) or alarmins. A pro-inflammatory cytokine, interleukin-1α (IL-1α) is known as a typical alarmin. IL-1α transmits signals by binding to IL-1 receptor 1 (IL-1R1), type I protein, expressed on the cell membrane of target cells, but detection of IL-1R1 at the protein and mRNA levels is difficult.

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Article Synopsis
  • Delayed eruption of permanent teeth is common, but impaction of the mandibular first molar is rare, often caused by issues like odontogenic cysts and tumors.
  • The article details two cases where odontogenic tumors led to the delayed eruption of the mandibular first molar in children, with specific diagnoses of ameloblastic fibro-odontoma and odontoma.
  • Treatment involved curettage of the tumors and fenestration of the impacted molars, which resulted in the successful eruption of the first molar in both cases.
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