Retrospective analysis of trauma patients transported by dispatch monitored type B ambulances to Dhulikhel Hospital, Kavre, Nepal, 2019-2023.

Background: Timely emergency medical services (EMS) are particularly important among trauma patients, as inefficient EMS systems can result in potentially avoidable death before reaching a hospital. The Dhulikhel Hospital Dispatch Center coordinates and monitors a growing network of ambulances, including seven Type B ambulances staffed with a trained prehospital care provider and medical equipment. This study evaluates the prehospital care and outcomes of trauma patients transported by Type B ambulances to Dhulikhel Hospital's Emergency Department, as monitored by the Dispatch Center.

Recognising vicarious trauma in research: the experiences of researchers who work with victimisation data and the support they need.

Background: The vicarious trauma people who provide direct clinical care may experience is well documented. However, there is limited information about the vicarious trauma that researchers working with victim-survivors of domestic and family violence (DFV) or victimisation-related data may experience.

Aim: To describe and reflect on the vicarious trauma experienced by people researching DFV who have repeatedly been exposed to significant, traumatic data.

A novel susceptibility locus to () identified by genetic mapping of automated microscopy computer vision data in grapevines.

Powdery mildew, caused by the fungus , is one of the primary causes of grape yield loss across the globe. While numerous resistance loci have been identified in various grapevine species, the genetic determinants of susceptibility to remain largely unexplored. Understanding the genetics of susceptibility for pathogenesis is equally important for developing durable resistance grapevines against this pathogen.

Comprehensive screening and analysis of pharmaceuticals and pharmaceutically active chemicals in wastewater: health and environmental hazards and removal efficiency of wastewater treatment plant in Malaysia.

Wastewater treatment plant (WWTP) is a sustainable technique for making wastewater reusable for non-potable purposes. However, in developing countries, most conventional WWTPs are not equipped to trap all pharmaceutical residues (PRs) and pharmaceutically active chemicals (PhACs). This study aims to perform non-target screening of these contaminants in wastewater and explore health and environmental hazards and the removal efficiency of a WWTP in Malaysia.

Primary Tracheal Schwannoma With Extension to the Thyroid Gland: Management.

The occurrence of neurogenic tumors in the tracheobronchial tree is uncommon. We report a case of transmural tracheal schwannoma with extraluminal component extending upto the left thyroid lobe. 40-year-old male presented with scanty hemoptysis due to transmural tracheal schwannoma with extraluminal part of tumor extending till the left lobe of thyroid gland.

Pre-breeding in alfalfa germplasm develops highly differentiated populations, as revealed by genome-wide microhaplotype markers.

Plant genebanks contain large numbers of germplasm accessions that likely harbor useful alleles or genes absent in commercial plant breeding programs. Broadening the genetic base of commercial alfalfa germplasm with these valuable genetic variations can be achieved by screening the extensive genetic diversity in germplasm collections and enabling maximal recombination among selected genotypes. In this study, we assessed the genetic diversity and differentiation of germplasm pools selected in northern U.

Assessing the drivers of sexual behavior among youth and its social determinants in Nepal.

Introduction: Sexual behavior among youth is a public health concern, particularly in contexts where cultural norms, socio-economic factors, and access to comprehensive sexual education play pivotal roles. This paper aims to examine the determinants of sexual behavior among Nepali youths.

Methods: This study analyzed data from 7,122 individuals aged 15-24 years from the Nepal Demographic and Health Survey (NDHS) 2022, focusing on a nationally representative sample.

Blood-brain barrier disruption and microglial activation during hypoxia and post-hypoxic recovery in aged mice.

Hypoxia triggers blood-brain barrier disruption and a strong microglial activation response around leaky cerebral blood vessels. These events are greatly amplified in aged mice which is translationally relevant because aged patients are far more likely to suffer hypoxic events from heart or lung disease, and because of the pathogenic role of blood-brain barrier breakdown in vascular dementia. Importantly, it is currently unclear if disrupted cerebral blood vessels spontaneously repair and if they do, whether surrounding microglia deactivates.

Impact of COVID-19 and recovery of routine diabetic retinopathy digital screening across different regions in England: an analysis of publicly available data.

Objective: This study aims to examine the reduction and subsequent recovery of routine digital screening (RDS) uptake in England from 2018 to 2022, exploring national, regional and individual Diabetic Eye Screening Programme (DESP) levels. The COVID-19 lockdown in most areas of England was from 26 March 2020 to 23 June 2020 (first national lockdown), 5 November 2020 to 2 December 2020 (second national lockdown) and 6 January 2021 to 8 March 2021 (third national lockdown).

Design: Retrospective data analysis.

Cross-sectional study on behavioural determinants associated with sugary foods and beverages and their correlates with body mass index among adolescents in Nagarjun municipality, Nepal.

Objectives: This study was conducted to determine the status of and factors associated with behavioural determinants (knowledge, attitude and practice) of sugary foods and beverages among adolescents in Kathmandu, Nepal.

Design: Cross-sectional study.

Setting: The study was done at educational institutions located in Nagarjun municipality, Kathmandu, Nepal.

Internet-delivered cognitive behaviour therapy for university students: Preference trial for various course durations.

Background: Internet-delivered cognitive behaviour therapy (ICBT) is an accessible and effective treatment option for post-secondary students, but engagement and completion rates are less favourable than in non-student populations in routine care. Studies on students' treatment preferences suggest that a range of options should be offered. Examining students' engagement and outcomes associated with ICBT course options of varying durations can help inform how to optimally deliver ICBT to university students in routine care.

A Systematic Review: The Impact of COVID-19 Policy Flexibilities on SNAP and WIC Programmatic Outcomes.

In response to the coronavirus disease 2019 (COVID-19) public health emergency (PHE), the federal government deployed policy flexibilities in food and nutrition assistance programs including the Supplemental Nutrition Assistance Program (SNAP) and Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) to meet the needs those experiencing economic hardship. Emergent literature evaluates the impact of these flexibilities on program outcomes. The objective of this study was to explore the impact of policy flexibilities deployed during the COVID-19 PHE on access, enrollment/retention, benefit utilization, and perceptions of SNAP and WIC.

Brain networks and intelligence: A graph neural network based approach to resting state fMRI data.

Resting-state functional magnetic resonance imaging (rsfMRI) is a powerful tool for investigating the relationship between brain function and cognitive processes as it allows for the functional organization of the brain to be captured without relying on a specific task or stimuli. In this paper, we present a novel modeling architecture called BrainRGIN for predicting intelligence (fluid, crystallized and total intelligence) using graph neural networks on rsfMRI derived static functional network connectivity matrices. Extending from the existing graph convolution networks, our approach incorporates a clustering-based embedding and graph isomorphism network in the graph convolutional layer to reflect the nature of the brain sub-network organization and efficient network expression, in combination with TopK pooling and attention-based readout functions.

Commercial Cellulosic Paper-Based Solid Electrolyte for High-Temperature Lithium-Sulfur Batteries.

Solid-state lithium-sulfur (Li-S) batteries show promise for future electric mobility due to their high energy density potential. However, high internal impedance, Li polysulfide shuttling, and dendrite formation exist. Herein, we present a Li-rich cellulosic solid-state electrolyte (SSE) that, when paired with a sulfurized polyacrylonitrile (SPAN) cathode, leads to durable Li-S batteries for use in the room temperature to 50 °C range.

Synthesis of Gold Nanoparticles Using Cucurbitacin E-Glycoside and Methyl Gallate Isolated from Citrullus colocynthis L. Fruit and Evaluation of their Antibacterial and Antibiofilm Activities.

Introduction: Metal nanoparticles have received much attention due to their unique physical dynamics, chemical reactivity, and promising biological applications. Green synthesis using natural compounds is an alternative to traditional chemical methods for the synthesis of nanoparticles.

Materials And Methods: Herein, two secondary metabolites were isolated from different fractions of methanolic extract of Citrullus colocynthis (bitter apple) Schard.

Lanthanide binding peptide surfactants at air-aqueous interfaces for interfacial separation of rare earth elements.

Rare earth elements (REEs) are critical materials to modern technologies. They are obtained by selective separation from mining feedstocks consisting of mixtures of their trivalent cation. We are developing an all-aqueous, bioinspired, interfacial separation using peptides as amphiphilic molecular extractants.

Butterfly Diversity and Community Dynamics in the Central Himalayas: Species Composition, Richness, Abundance, and Seasonal Variation of Butterflies (Lepidoptera: Papilionoidea) in Bhorletar, Nepal.

Butterflies are among the most effective bioindicators of climate change; however, their diversity in many rural areas of the Central Himalayas remains understudied. This study provides an assessment of butterfly diversity in the foothills of Bhorletar, Madhya Nepal Municipality, Lamjung District, Nepal, within an elevation range of 420-600 m. Conducted between July 2019 and January 2021, the survey involved opportunistic observations and photography of adult butterflies in their natural habitats, with sampling occurring six times each month.

Novel two-parameter quadratic exponential distribution: Properties, simulation, and applications.

This research paper introduces a novel two-parameter quadratic exponential distribution (NTPQED), thoroughly examining its statistical properties and practical applications. The study delves into essential characteristics of the distribution, including its asymptotic behavior, moments, order statistics, and entropies. Additionally, we present fuzzy reliability, value at risk, mean excess function, limited expected value function, tail value at risk, and tail variance.

"Reactive" Chemical Strategy to Attain Substrate Independent "" Omniphobic Solid Anti-Biofouling Coatings.

Covalent and defect-free surface-grafted solid lubricating chains that can impart slippery behavior have proven advantageous over lubricant infused and textured anti-wetting surfaces. Herein, the co-hydrolysis and co-condensation of a mixture of organosilanes followed by the epoxy-amine ring opening reaction at the interface results in a highly robust, transparent and solid slippery omniphobic coating (LL-OSC). The presence of the epoxy-terminated organosilane a) acts as a molecular spacer in between the low-surface energy, rigid fluorine terminated silane and b) provides 'reactive' epoxy groups for covalent binding to a pre-functionalized amine surface for potential applicability in droplet transport and manipulation, diagnostics etc.

Effectiveness of Osteoarthritis Management Program (OAMP) on the Level of Knowledge and Practice Regarding Self-Management Among Elderly with Osteoarthritis.

Objectives: To assess the effectiveness of osteoarthritis management program (OAMP) on the level of knowledge and practice regarding self-management among elderly with OA.

Materials And Methods: A quasi-experimental study was conducted among 60 elderly with osteoarthritis (OA) from March 1, 2021, to March 29, 2021. A community-based survey was conducted to identify the elderly with OA, and 60 persons were selected by using simple random technique.