Publications by authors named "Macarena Roa"
Article Synopsis
- Patients with immunodeficiency are at a higher risk of developing certain cancers, particularly mature lymphoid neoplasms and lymphoproliferative disorders.
- A 50-year-old woman on immunosuppressive therapy for dermatomyositis presented with swollen lacrimal glands, weight loss, and night sweats, leading to an elective biopsy.
- Post-surgery, she experienced acute abdominal issues that revealed multiple organ lesions and ultimately led to a diagnosis of polymorphic B-lymphoproliferative disorder resembling lymphomatoid granulomatosis, a rare condition linked to immunosuppression.
Real-world experience in older patients with diffuse large B-cell lymphoma treated in Latin America: A study by the Latin American study group of lymphoproliferative disorders (GELL).
Myrna Candelaria Luis Villela Maria-Alejandra Torres-Viera Camila Peña Macarena Roa Efeen Montaño-Figueroa
J Geriatr Oncol
September 2023
Primary plasma cell leukemia (pPCL) is an infrequent and aggressive plasma cell disorder. The prognosis is still very poor, and the optimal treatment remains to be established. A retrospective, multicentric, international observational study was performed.
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- * The incidence rate was significantly lower in the Amerindian population (0.09/100,000) compared to the general Chilean population (1.17/100,000), with a median patient age of 73 years at diagnosis.
- * Overall survival (OS) at five years was 56%, with poorer outcomes observed in men, patients aged 65 and older, and those classified as high-risk, indicating lower incidence and worse
Article Synopsis
- The study examined the clinical and survival characteristics of transplant-eligible multiple myeloma patients in Latin America, focusing on the differences between public and private healthcare systems.
- It included data from 1293 patients diagnosed from 2010 to 2018, highlighting significant disparities in outcomes and survival rates between those treated in public versus private institutions.
- The findings suggest that late diagnosis and limited access to effective treatments in public facilities contribute to poorer survival rates, while patients receiving modern therapies and autologous stem cell transplants have survival rates comparable to international standards.
Background: Primary plasma cell leukemia (pPCL) is uncommon, aggressive and has a different biology than multiple myeloma (MM).
Aim: To report the features of patients with pPCL.
Material And Methods: Review of databases of the Hematology Department and the Hematology laboratory.
Article Synopsis
- Trauma is a major cause of death among young adults, leading to a study focused on trauma patients in an ICU in Santiago, Chile.
- The study included 72 patients, primarily male, with polytrauma or severe injuries, revealing that traumatic brain injuries were the most common.
- Results showed a mortality rate of 15% in the ICU and 25% in the hospital, consistent with international findings despite similar treatment and evolution for polytrauma and severely traumatized patients.