Development and validation of a nomogram incorporating gene expression profiling and clinical factors for accurate prediction of metastasis in patients with cutaneous melanoma following Mohs micrographic surgery.

Background: There is a need to improve prognostic accuracy for patients with cutaneous melanoma. A 31-gene expression profile (31-GEP) test uses the molecular biology of primary tumors to identify individual patient metastatic risk.

Objective: Develop a nomogram incorporating 31-GEP with relevant clinical factors to improve prognostic accuracy.

Penile Squamous Cell Carcinoma: Penis-Preserving Treatment With Mohs Micrographic Surgery.

Background: There have been few published case series of penile squamous cell carcinoma (SCC) removed with Mohs micrographic surgery (MMS). Of these case series, the published cure rates are between 68% and 74%.

Objective: To report 30 years of experience removing penile SCCs with MMS.

Effectiveness and Advantages of On-Site Pathology Services in the Care of Patients With Nonmelanoma Skin Cancer.

Background: On-site pathology services are an integral part of many dermatology and surgical dermatology practices in the United States.

Objective: Assess the effectiveness and advantages of on-site pathology services.

Methods: Biopsy data from 7 practices with on-site pathology services were reviewed to determine the diagnostic accuracy of malignancies from all lesional biopsies.

Recurrent basal cell carcinoma with intracranial invasion: a case report and literature review.

Basal cell carcinoma (BCC) is the most common malignancy in humans. We present a man with a recurrent BCC of the scalp that presented as an intracranial tumor 18 years after original excision.

How accurate are the suggested diagnoses on biopsy requisitions for inflammatory skin disease? A retrospective study of 348 cases.

Clinical information is often critical to the histopathologic interpretation of cutaneous biopsies for inflammatory skin diseases. This information is often conveyed to the dermatopathologist as list of possible diagnoses. We reviewed 348 cases of biopsied inflammatory skin disease and measured the correlation between the original clinical differential diagnoses on the pathology requisition and the patient's final diagnosis.

Necrotizing infundibular crystalline folliculitis manifesting as a perforating mucinosis: a case report.

: Necrotizing infundibular crystalline folliculitis (NICF) is a rare entity manifesting as waxy folliculocentric papules comprised of filamentous birefringent crystalline deposits. We report a case of NICF in an 85-year-old man, presenting as gritty, cream-colored, and erythematous papules across the midline back. Biopsy demonstrated a pale plug comprised of copious mucin.

Letter: Basal cell carcinoma with vascular invasion.

Non-melanoma skin cancer (NMSC) is the most common cancer in humans. Basal cell carcinoma accounts for 75 percent to 80 percent of NMSC. We report a primary cutaneous BCC on the upper chest in which vascular invasion was demonstrated by histopathology and the unique application of dual immunohistochemistry.

Cutaneous mixed tumor with extensive chondroid metaplasia: a potential mimic of cutaneous chondroma.

True cutaneous chondromas are extremely rare. Previously they have reportedly been confused with soft tissue chondromas and cartilaginous developmental anomalies. Monophasic mixed tumor could potentially also be mistakenly diagnosed as a true cutaneous chondroma.

Letter: Adenocarcinoma of the lung associated with pityriasis rubra pilaris.

We describe a case of pityriasis rubra pilaris refractory to conventional treatment, found to be associated with an unrecognized primary adenocarcinoma of the lung. Complete resolution of the eruption followed surgical resection of the tumor.