[Genetic characterization of the interleukin 1 b polymorphisms -511, -31 y +3954 in a Colombian population with dyspepsia].

Introduction: The human interleukin-1b gen (IL-1 b) polymorphisms such as -511, -31 and +3954 have been associated with the presence of gastric cancer, due to the inhibitor effect that this protein has on acid secretion in the stomach. This facility can enhance the colonization and infection by agents like Helicobactor. pylori and the genesis of preneoplastic states that can lead to cancer development.