Publications by authors named "Maaz Amir"
Article Synopsis
- Cardiovascular diseases are a top cause of death for women, yet they are frequently underestimated and not adequately addressed in healthcare.
- The review discusses the unique challenges women face in terms of diagnosis, risk factors related to hormonal changes, and the need for tailored prevention strategies that consider sex-specific issues.
- It advocates for a collaborative, multidisciplinary approach to enhance awareness, improve treatment options, and ultimately better health outcomes for women with cardiovascular disease.
Non-small cell lung carcinoma (NSCLC) is a prevalent and aggressive form of lung cancer, with a poor prognosis for metastatic disease. Immunotherapy, particularly immune checkpoint inhibitors (ICIs), has revolutionized the management of NSCLC, but response rates are highly variable. Identifying reliable predictive biomarkers is crucial to optimize patient selection and treatment outcomes.
View Article and Find Full Text PDFInfective endocarditis caused by species is increasingly recognized as an emerging clinical entity. species are fastidious gram-positive cocci that are typically commensal organisms but can become opportunistic pathogens. This systematic review aimed to provide a comprehensive overview of endocarditis due to species by synthesizing existing evidence.
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- Alzheimer's disease (AD) is a serious neurodegenerative disorder marked by cognitive decline, driven by amyloid-beta plaques and tau protein, which leads to neuronal damage and inflammation.
- Quantum dots (QDs) are highlighted as innovative nanotechnology tools that show promise for both diagnosing and treating AD due to their unique properties and ability to target multiple aspects of the disease.
- The systematic review compiled evidence from 20 studies on QDs, revealing their capabilities in inhibiting toxic protein aggregation and facilitating real-time imaging, while also noting challenges in biocompatibility and clinical application that need to be addressed.
Pancreatic ductal adenocarcinoma (PDAC) is a formidable global health concern with a dire prognosis, highlighting the critical need for early detection strategies. This systematic review delves into the potential of salivary biomarkers as a non-invasive means for identifying PDAC at its incipient stages. Saliva's proximity to the circulatory system enables the detection of tumor-derived biomolecules, making it an ideal candidate for mass screening.
View Article and Find Full Text PDFIn the realm of oncology, the prognosis and treatment of triple-negative breast cancer (TNBC) have long been challenges for researchers and clinicians. Characterized by its aggressive nature and limited therapeutic options, TNBC demands innovative approaches to understanding its underlying mechanisms and improving patient outcomes. One such avenue of exploration that has emerged in recent years is the study of ferroptosis, a form of regulated cell death driven by iron-dependent lipid peroxidation.
View Article and Find Full Text PDFA Systematic Review of the Neuroprotective Effects of Vascular Endothelial Growth Factor (VEGF) in Diabetic Retinopathy and Diabetic Macular Edema: Unraveling the Molecular Mechanisms and Clinical Implications.
Cureus
December 2023
Article Synopsis
- * Recent studies have shown that vascular endothelial growth factor (VEGF), known for its role in blood vessel growth, also has potential neuroprotective effects on retinal cells.
- * This review highlights the need for more research into VEGF's complex roles and its impact on treatment strategies, as current anti-VEGF therapies may negatively affect retinal ganglion cell survival.