Publications by authors named "Maayan Ben Sasson"

Introduction: Millions of persons with chronic pain across North America and Europe use opioids. While the immunosuppressive properties of opioids are associated with risks of infections, these outcomes could be mitigated through careful patient selection and monitoring practices when appropriate. It is important to recognise that some patients do benefit from a carefully tailored opioid therapy.

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Differential diagnosis is a crucial aspect of medical practice, as it guides clinicians to accurate diagnoses and effective treatment plans. Traditional resources, such as medical books and services like UpToDate, are constrained by manual curation, potentially missing out on novel or less common findings. This paper introduces and analyzes two novel methods to mine etiologies from scientific literature.

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Article Synopsis
  • * Recent studies have identified other mutations, like those in PIK3CA, which may also drive LCH independently from MAPK signaling, although their effects were not fully understood until now.
  • * New research using a mouse model shows that PIK3CA mutations can contribute to LCH, and a patient's LCH with this mutation successfully responded to a targeted treatment (alpelisib), highlighting the potential for personalized therapies in treating histiocytic neoplasms.
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