Publications by authors named "Maarten J M Vinken"
Lymph node staging with fluorine-18 prostate specific membrane antigen 1007-positron emission tomography/computed tomography in newly diagnosed intermediate- to high-risk prostate cancer using histopathological evaluation of extended pelvic node dissection as reference.
Rick Hermsen Esmée B C Wedick Maarten J M Vinken Ludwike W M van Kalmthout Heidi V N Küsters-Vandevelde
Eur J Nucl Med Mol Imaging
September 2022
Article Synopsis
- F-PSMA-1007 is a radiotracer for prostate cancer staging that lacks large validation studies for its diagnostic accuracy compared to traditional methods like histopathology.
- A trial evaluated 99 men with intermediate to high-risk prostate cancer, measuring the sensitivity and specificity of F-PSMA-1007 PET/CT against lymph node dissection results.
- The results indicated high specificity (89.9%) but moderate sensitivity (53.3%), suggesting that while it’s effective for certain detections, it shouldn’t replace extensive surgical procedures for accurate staging.