Comparative efficacy of mandibular advancement devices in obstructive sleep apnea: a network meta-analysis.

Purpose: To analyze relative efficacies of mandibular advancement devices (MAD) in sleep apnea treatment.

Methods: From eligible randomized controlled trials (RCT), MADs were classified based on their mechanistic designs. Data on apnea-hypopnea index (AHI), Epworth sleepiness scale (ESS), nadir oxygen saturation (minSaO), and sleep efficiency (SE%) from RCTs were then analyzed in network meta-analyses, and relative ranking of different MADs was computed based on P scores (a method of ranking similar to SUCRA).