Persistence of multidrug-resistant Staphylococcus haemolyticus in an animal veterinary teaching hospital clinic.

In the recent decades, coagulase-negative staphylococci (CNS) have emerged as important nosocomial pathogens with the ability to develop resistance to antibiotics and disinfectants. Multidrug-resistant CNS are currently a common finding in hospital settings and hospitalized patients. Little is known about the occurrence and persistence of multidrug-resistant CNS in animal clinics.

Resistance to quaternary ammonium compounds in food-related bacteria.

Microbial resistance to antimicrobial agents continues to be a major problem. The frequent use and misuse of disinfectants based on quaternary ammonium compounds (QACs) in food-processing industries have imposed a selective pressure and may contribute to the emergence of disinfectant-resistant microorganisms. A total number of 1,325 Gram-negative isolates (Escherichia coli, other coliforms Vibrio spp.

Frequency of disinfectant resistance genes and genetic linkage with beta-lactamase transposon Tn552 among clinical staphylococci.

A total of 61 strains of Staphylococcus aureus and 177 coagulase-negative staphylococcal strains were isolated from the blood of patients with bloodstream infections and from the skin of both children under cancer treatment and human immunodeficiency virus-positive patients. The MIC analyses revealed that 118 isolates (50%) were resistant to quaternary ammonium compound-based disinfectant benzalkonium chloride (BC). The frequencies of resistance to a range of antibiotics were significantly higher among BC-resistant staphylococci than among BC-sensitive staphylococci.