Human Brain Deuterium Metabolic Imaging at 7 T: Impact of Different [6,6'-H]Glucose Doses.

Background: Deuterium metabolic imaging (DMI) is an innovative, noninvasive metabolic MR imaging method conducted after administration of H-labeled substrates. DMI after [6,6'-H]glucose consumption has been used to investigate brain metabolic processes, but the impact of different [6,6'-H]glucose doses on DMI brain data is not well known.

Purpose: To investigate three different [6,6'-H]glucose doses for DMI in the human brain at 7 T.