The study aimed to explore how Axin regulates the ability of lymphoma cells to invade and migrate, focusing on the underlying molecular mechanisms.
Utilizing techniques like RT-PCR and Western blotting, researchers analyzed the expressions of Axin and related proteins in various lymphoma cell lines.
Findings indicated that higher levels of Axin lead to reduced expressions of β-catenin, MMP7, and MMP9, suggesting that Axin plays a crucial role in suppressing the invasive and migratory capabilities of lymphoma cells.