Publications by authors named "Ma Xiyan"
Background And Aims: Early stage administration of Paxlovid has been shown to improve the prognosis of mild to moderate COVID-19 patients with high risk. However, few evidence was validated in severe COVID-19 patients with hypoxemia. It is also unclear whether delayed usage of Paxlovid affected prognosis in COVID-19 patients or not.
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- Metabolic syndrome is influenced by various factors such as lifestyle and mood, and effective self-management can help reduce disease progression.
- A study reviewed 25 research articles, focusing on stress management interventions for patients with metabolic syndrome suffering from psychological issues, using meta-analysis techniques.
- The findings showed that stress management interventions yielded significant improvements in health outcomes like depression, blood glucose levels, cholesterol, self-management behaviors, and overall quality of life.
Background: Hypoxic pulmonary hypertension (HPH) is a common complication of chronic lung disease, which severely affects the survival and prognosis of patients. Several recent reports have shown that DNA damage and repair plays a crucial role in pathogenesis of pulmonary arterial hypertension. DNA-dependent protein kinase catalytic subunit (DNA-PKcs) as a part of DNA-PK is a molecular sensor for DNA damage that enhances DSB repair.
View Article and Find Full Text PDFFive sesquiterpenoids, 1α,8α-epidioxy-4α-hydroxy- 5αH-guai-7(11),9-dien- 12,8-olide. (1), 8,9-seco-4β-hydroxy-1α,5βH-7(11)-guaen-8,10-olide (2), 8α-hydroxy-1α, 4β,7βH-guai-10(15)-en- 5β,8β-endoxide(3), 7β,8α-dihydroxy-1α,4αH-guai-10(15)-en-5β,8β-endoxide(4) and 7-hydroxy-5(10),6,8-cadinatriene-4-one(5), together with seven known analogs were isolated from the rhizomes of Curcuma wenyujin. Their structures and relative configurations were determined on the basis of spectroscopic methods including 2D NMR techniques, and the structures of 1 and 2 were confirmed by single-crystal X-ray diffraction experiment.
View Article and Find Full Text PDFObjective: To study the triterpenoid saponins in Hemsleya chensnsis.
Method: The chemical constituents were isolated and purified by various chromatographic methods and their structures were elucidated on the basis of spectral analysis.
Result: Seven known triterpenoid saponins were isolated from the root of H.