Background: Epidemiological studies of acute otitis media (AOM) are scarce and no prospective studies have been performed in Spain.
Objectives: To describe the incidence of AOM in the first year of life and its associated risk factors, with special focus on air pollution.
Methods: We performed a prospective cohort study of 229 newborn infants during the first year of life stratified by pollution zones, and followed-up by their pediatricians in their health center.