Glassy carbon electrodes modified with composites of starburst-PAMAM dendrimers containing metal nanoparticles for amperometric detection of dopamine in urine.

Composites of hydroxyl-terminated PAMAM dendrimers, generation 4.0 (64 peripheral OH groups) containing either Ir, Pt or Rh nanoparticles were synthesized and characterized in solution. Each one of these composites was then immobilized on a glassy carbon electrode (GC) and incorporated as an amperometric detector for dopamine in a high-performance liquid chromatograph (HPLC).