Publications by authors named "Ma Dolores Chirlaque"
Background: Parkinson's disease (PD) is a progressive neurodegenerative disorder, diagnosed according to the clinical criteria that occur in already advanced stages of PD. The definition of biomarkers for the early diagnosis of PD represents a challenge that might improve treatment and avoid complications in this disease. Therefore, we propose a set of reliable samples for the identification of altered metabolites to find potential prognostic biomarkers for early PD.
View Article and Find Full Text PDFBackground: Information on the validity of self-reported cases of stroke and acute myocardial infarction (AMI) is varied. The aim of this study was to assess the validity and agreement of self-reported prevalent cases of stroke and AMI in the Spanish cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC).
Methods: At recruitment, 1992-1996, and in the follow-up (3 years after recruitment), each participant in the Spanish EPIC cohort (15,630 men and 25,808 women) was asked if a doctor had ever said that they had had a stroke or AMI, and the results were compared with information available in medical records.
Article Synopsis
- This study explores the relationship between sex steroid hormone levels and breast cancer risk in premenopausal women using data from the European Prospective Investigation into Cancer and Nutrition cohort.
- The research measured various hormones (such as testosterone, androstenedione, DHEAS, and progesterone) in serum samples from women who developed breast cancer and matched controls to determine potential risk factors.
- Findings indicate that higher levels of testosterone, androstenedione, and DHEAS are linked to increased breast cancer risk, while higher progesterone levels may reduce the risk, suggesting complex hormonal influences on breast cancer development.