A Toxic Environment: a Growing Understanding of How Microbial Communities Affect Escherichia coli O157:H7 Shiga Toxin Expression.

Enterohemorrhagic (EHEC) strains, including O157:H7, cause severe illness in humans due to the production of Shiga toxin (Stx) and other virulence factors. Because Stx is coregulated with lambdoid prophage induction, its expression is especially susceptible to environmental cues. Infections with Stx-producing can be difficult to model due to the wide range of disease outcomes: some infections are relatively mild, while others have serious complications.

A Putative Microcin Amplifies Shiga Toxin 2a Production of Escherichia coli O157:H7.

O157:H7 is a foodborne pathogen implicated in various multistate outbreaks. It encodes Shiga toxin on a prophage, and Shiga toxin production is linked to phage induction. An strain, designated 0.

Low-density lipoprotein composition and oxidability in atherosclerotic cardiovascular disease.

Objectives: To characterize low-density lipoprotein (LDL) chemical composition and oxidability in normolipidemic and dyslipidemic patients with atherosclerotic cardiovascular disease, as compared with matched control subjects. To evaluate LDL susceptibility to oxidation, we determined the cutoff points of thiobarbituric reactive substances (TBARS) in LDL after oxidative stress, as well as its resistance to oxidation.

Design And Methods: LDL (density 1.

[President Agustin P. Justo and the Faculty of Medicine: other times].

In January this year it was the 50 anniversary of Gral. Agustin P. Justo death, who was President of Argentine during the period 1932-1938.

Evaluation of the high density lipoprotein cholesterol protective effect against atherogenesis in rabbits fed cholesterol supplemented diets.

Plasma high density lipoprotein cholesterol (HDL-C) was evaluated in 15 rabbits fed cholesterol supplemented diets to assess its protective effect on the atherogenic process. From a baseline level of 29 +/- 11 mg/dl (mean +/- SD) the maximum attained for HDL-C was twofold in only three rabbits, whereas total cholesterol (TC) increased 20 fold. Plasma TC/HDL-C ratio rose 80 fold from the baseline (2.

Swallowing-dependent atrial tachyarrhythmias. Their mechanism.

We describe here the case of one patient who exhibited several types of atrial tachyarrhythmias induced by swallowing. There was no evidence of other cardiac or gastroesophagic abnormalities. The electrophysiologic study demonstrated a second degree A-V block due to block within the atria.