An amylase-producing serous cystadenocarcinoma of the ovary.

A patient with an amylase-producing serous cystadenocarcinoma of the ovary had elevated serum and urine amylase levels and high levels of amylase in pleural and ascitic fluids. Serum and urine amylase levels reflected both surgical removal of tumor mass and response to chemotherapy. Tumor homogenates had pronounced amylase activity.

Hemi-replacement arthroplasty of the proximal humerus. A case report.

A ten-year-old girl underwent excision of a chondrosarcoma of the right proximal humerus with subsequent insertion of a prosthesis. Failure of the device occurred six years after operation, requiring revision to an identical but shorter prosthesis. This device failed 1 1/2 years later and was replaced by a fibular graft inserted in the humeral medullary canal.

Immunohistochemical demonstration of ribonuclease and amylase in normal and neoplastic parotid glands.

Antibodies specific for bovine ribonuclease A (antiRNase A) were raised in rabbits, and immunologic cross-reactivity between bovine RNase A and human salivary gland RNase was demonstrated. The antiRNase A served as the primary antibody in the peroxidase-antiperoxidase immunohistochemical technique. Paraffin blocks of five normal human parotids and 20 parotid tumors were examined.

Treatment of genu recurvatum by proximal tibial closing-wedge/anterior displacement osteotomy.

An operation is described for correction of the osseous form of genu recurvatum, which is secondary to premature closure of the anterior part of the proximal tibial physis with continued growth of the posterior part. At the Alfred I. duPont Institute 14 patients with 17 involved knees have been treated surgically for osseous genu recurvatum.

Severe measles: some unanswered questions.

The severity of measles is greatest in the developing countries, where a high proportion of children have nutritional deficiencies. Nutritional deficiencies may play a part in the complications that result from measles infection. Nutritional deficiencies may also be the reason for the young age at which infection is found in children in developing countries; the child with severe measles and an immune system that is suppressed as a result of malnutrition secrets the virus three times longer than does a child with normal nutrition.

Uptake of uranium, molybdenum, copper, and selenium by the radish from uranium-rich soils.

Radishes were grown in the naturally occurring uranium-containing soils found in the Okanagan Valley of British Columbia. The movement of uranium, molybdenum, copper, and selenium from the soil to the roots and the above-ground plant was investigated. Bioaccumulation was not observed for uranium, copper, and with some exceptions, selenium.

Papillary serous carcinoma of the retroperitoneum.

We describe a retroperitoneal neoplasm in an 11-year-old girl which had a light microscopic appearance identical to that of papillary serous carcinoma of the ovary. There was no evidence of ovarian involvement. Immunohistochemical staining for amylase was positive within the cytoplasm of tumor cells.

Hyperexplexia: an inherited disorder of the startle response.

A family is presented with hyperexplexia, a rare autosomal dominant neurological disorder. Affected individuals manifest flexor hypertonia and hypokinesia during infancy. Later and throughout life, the condition is characterized by exaggerated involuntary myoclonic startle reactions, which on occasion result in falling.

Distance learning for primary health care.

The United Nations' stated objective is to bring primary health care to all by the year 2000. To reach this goal, the health profession will have to be involved in a greater change than has ever taken place since the introduction of scientific medicine. Important advances in educational methods offering many advantages for developing countries have taken place.