Dentoskeletal effects of molar distalization with miniscrew-anchored cantilever and pendulum appliance for Class II correction.

Introduction: The objective of this study was to compare the dental and skeletal changes promoted by the miniscrew-anchored cantilever and pendulum appliance for Class II correction.

Methods: This retrospective study involved 52 patients with Class II malocclusion divided into 2 groups according to the treatment received: the miniscrew group (MG) with 23 patients (14 females and 9 males; mean initial age of 12.42 years) treated using the miniscrew-anchored cantilever, and the pendulum group (PG) with 29 patients (21 females and 8 males; mean initial age of 13.

Multidisciplinary Oral Rehabilitation of Complex Frontonasal Dysplasia: A Case Report.

This case report presents the multidisciplinary treatment of a male patient with a complex form of frontonasal dysplasia who presented with a 0 to 14 facial cleft, mild hypertelorism, absence of the nasal medial process of the nose, and frontonasal encephalocele. Cranial and plastic surgeries were performed to correct hypertelorism and improve the esthetic appearance of the frontonasal region. In the permanent dentition, the patient presented a Class II, division 1 malocclusion with severe maxillary constriction and bilateral posterior crossbite.

Bioactive-based spray and spot-on formulations: Development, characterization and in vitro efficacy against fleas and ticks.

The flea Ctenocephalides felis felis and the tick Rhipicephalus sanguineus are ectoparasites of great importance in veterinary medicine that can affect pets, also impacting the lives of owners due to the possible transmission of zoonoses. Due to the negative impact on animals, owners and the environment, synthetic chemicals are being replaced by natural alternatives. Eugenol and carvacrol stand out as bioactive substances with potential antiparasitic activity.

Construction and validation of an educational game on biosafety in the central sterile supply department.

Objectives: to construct and validate an educational game on biosafety in the Central Sterile Supply Department of a hospital in Curitiba, PR.

Methods: the study was conducted using a quantitative approach, employing applied and technological research with an exploratory design. The process was divided into six stages, from the definition of the theme to the validation and application of the game.

Maxillary protraction anchored on miniplates versus miniscrews: three-dimensional dentoskeletal comparison.

Objective: This retrospective study aimed to compare the three-dimensional (3D) outcomes of the novel miniscrew-anchored maxillary protraction (MAMP) therapy and the bone-anchored maxillary protraction (BAMP) therapy.

Methods: The sample comprised growing patients with skeletal Class III malocclusion treated with two skeletal anchored maxillary protraction protocols. The MAMP group comprised 22 patients (9 female, 13 male; 10.

Orthopedic or Surgical Treatment in Gartland Type II Supracondylar Humerus Fractures: A Systematic Review.

Background: There is a broad consensus among orthopedic surgeons in the treatment of Gartland type I supracondylar humerus fractures (conservative) and Gartland type III (surgical) fractures, but there is controversy regarding the treatment of choice for Gartland type II fractures. The aim was to analyze the existing current evidence on the choice of surgical or conservative treatment of Gartland type II supracondylar humerus fractures.

Methods: A systematic review was carried out following the PRISMA guidelines.

Organic Sulfur Markers as Proxies of Depositional Paleoeenvironments Related to Recôncavo and Amazon Basins, Brazil.

This study employed organic sulfur markers (S-markers) associated with geochemistry parameters to evaluate the paleoenvironment of different depositional settings in 24 samples collected in vertical sections of outcrops of the Candeias and Barreirinha Formations in Recôncavo and Amazon basins, respectively. A total of twenty-one S-markers from benzothiophene (BT), dibenzothiophene (DBT), and benzonaphtothiophenes (BNT) classes were optimized and quantified by gas chromatography-triple quadrupole mass spectrometry (GC-MS/MS). S-markers efficiently evaluated and differentiated the depositional paleoenvironment in the source rocks based on the individual compound, in cross-validation with saturated biomarkers, and associated with parameters such as total organic carbon (TOC) and Rock-Eval pyrolysis.

Cholecystectomy Is a Risk Factor for Proximal Colon Cancer That May Also Relate to its Aggressiveness.

Introduction: There are studies with mixed conclusions about the role cholecystectomy plays as a risk factor for proximal colorectal cancer (CRC).

Methods: We performed a multicenter retrospective cohort study where the records of patients with CRC were reviewed. Data was collected regarding affected colon subsegment (cecum, ascending, transverse, descending, sigmoid, or rectum, which were also combined into proximal or distal colon), history and time since cholecystectomy, histopathology reports (TNM classification and clinical stage), and KRAS, NRAS, and BRAF mutation analysis.

Comparison of aging of nonextraction treated and normal untreated occlusions: 40-year follow up.

The objective of this study was to compare the aging changes of the dental arches in patients treated without extractions and untreated normal occlusion subjects after a four-decade follow-up. This retrospective study evaluated two groups: The Treated Group (Group T) comprised 16 patients (6 male; 10 female) presenting with Class I or Class II malocclusions treated orthodontically without extractions. Dental models were evaluated 3 stages: T1 (pretreatment, 13.

CRISPR-Cas systems in enterococci.

Enterococci are members of the microbiota of humans and other animals. They can also be found in the environment, associated with food, healthcare infections, and hospital settings. Due to their wide distribution, they are inserted in the One Health context.

Impact of Etonogestrel-releasing contraceptive implant use in cisgender women with Sickle cell disease.

Background: Sickle cell disease is a hereditary hemolytic anemia that exposes women to increased health risks especially in pregnancy, with serious implications for the woman and fetus. Acute pain episodes can occur multiple times per month and result in reduction of quality of life and disruption of her life.

Objective: To assess the clinical, including pain and metabolic parameters of women with sickle cell disease using etonogestrel-releasing contraceptive implants.

HIV serodifference: the "unsaid" in the social representations of health professionals.

Objective: To analyze social representations from the perspective of the silent zone of health professionals regarding HIV serodifference.

Method: This is a qualitative study, based on the theoretical-methodological framework of Social Representations, with the Theory of the Central Nucleus and Mute Zone by Jean Claude Abric. 51 professionals from specialized services from the metropolitan region of a capital in the northeast of Brazil participated, from October to December 2020.

Long-term predominance in childhood colonization of the multidrug-resistant lineage 6C/ST386 of Streptococcus pneumoniae after universal immunization with the 10-valent pneumococcal conjugate vaccine in Brazil.

Background: A study conducted in the city of Niterói/RJ, four years after the introduction of the pneumococcal conjugate vaccine in Brazil, reported the emergence of non-vaccine serotype 6C Streptococcus pneumoniae associated with carriage in children. The multidrug-resistant (MDR) lineage ST386 was predominant among 6C isolates. A subsequent study, in 2019, reported the continued prevalence of 6C as the main serotype.

Salivary gland secretory carcinoma: A case presentation in minor salivary gland with review.

Introduction And Importance: Salivary gland secretory carcinoma (SGSC) represents a rare malignant tumor of the salivary glands. Despite being regarded as low-grade tumors, they may manifest with metastases and a high-grade aggressive clinical behaviour. The literature on this subject is limited, and there is currently no standardized approach to treatment.

Orthodontic Analysis behind the Extraction of Hypomineralised First Molars.

This chapter will discuss the orthodontic perspective of extractions of compromised first permanent molars (cFPMs) due to hypomineralisation. The context behind the diagnosis of a poor prognosis of cFPM that would support the planning of extractions will be presented. In addition, the ideal timing for interceptive extraction of cFPM as well as the favorable and unfavorable orthodontic scenarios for extractions in the permanent dentition will be discussed.

An Integrated Assessment of Different Depositional Paleoenvironment Using Nitrogen Markers and Biomarkers after Chromatographic Methods Optimization.

In this study, chromatographic methods were first optimized to ensure the robustness of the identification and quantification of nitrogen markers and biomarkers. Then, the optimal conditions were applied to 14 crude oil samples deposited in distinct paleoenvironments from Brazil, Venezuela, and Colombia to perform an integrated geochemical assessment. Analytical standards, certified reference material, and retention indices were used to confirm the identification of biomarkers and N-markers.

Curio: A Dataflow-Based Framework for Collaborative Urban Visual Analytics.

Over the past decade, several urban visual analytics systems and tools have been proposed to tackle a host of challenges faced by cities, in areas as diverse as transportation, weather, and real estate. Many of these tools have been designed through collaborations with urban experts, aiming to distill intricate urban analysis workflows into interactive visualizations and interfaces. However, the design, implementation, and practical use of these tools still rely on siloed approaches, resulting in bespoke systems that are difficult to reproduce and extend.

Larger Than Life? Body Mass Records of Zoo-Managed Giant Anteaters (Myrmecophaga tridactyla).

It has been suggested repeatedly that zoo-kept giant anteaters (Myrmecophaga tridactyla) have higher body masses than their free-ranging conspecifics. Here, we assess this hypothesis by comparing body mass data of 184 female and 173 male individuals kept in zoos to published and unpublished data of free-ranging animals (n = 215). In zoos, the average adult body mass of all individuals was 45.

Comparison of alveolar bone morphology after expansion with hybrid and conventional Hyrax expanders.

Objectives: To compare the buccal and palatal bone changes of maxillary posterior teeth produced by hybrid hyrax (HH) and conventional hyrax (CH) expanders in growing patients.

Material And Methods: A sample of 32 patients with posterior crossbites in the late mixed dentition was recruited and randomly allocated into two groups. Group HH was composed of 18 individuals with a mean age of 10.

Development and Content Validation of a Nursing Clinical Simulation Scenario on Transfusion Reaction Management.

Blood transfusion is a life-saving procedure widely used in healthcare. However, complications such as transfusion reactions may occur. Knowledge of these reactions is essential for patient safety.