Publications by authors named "MINETTO E"

We have reported a "benign metastasizing uterine leiomyoma" case in a 55-year-old woman still living with "benign" metastases (lung, skin, lymph nodes, bone and perhaps the brain) 14 years after the first uterine myomectomy.

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The characteristics of the immunological picture give some concepts and judgement elements about the combined diseases. On this subject, the significant index of higher tuberculosis incidence in patients with silicosis is paradigmatic. Furthermore chronic dismetabolisms and gamma-globulins immunodeficiencies support tuberculosis developing.

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The behaviour of lymphocyte sub-populations and lymphocyte electrophoretic mobility has been studied in seven patients with agamma/hypogammaglobulinaemia before and after gammaglobulin therapy.

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This case (a young man) presented a clinical picture of a hard periorbital edema, hepatosplenomegaly and a mild bilateral pulmonary fibrosis. The histopatological pattern of our case (as well as his sister affected with the same syndrome) was characterized by the presence of macrophages full of blue staining granules and bone marrow macrophagic infiltrations. In the pulmonary function tests the volumes and compliance test and diffusing capacity were normal.

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The favorable results obtained by other authors with polichemotherapy encouraged us to employ therapeutic scheme using a combination of 4 drugs. Treatment envolved the administration of 300 mg/mz cyclophosphamide, 350 mg/m2 5-fluorouracil, 10 mg/mw2 methotrexate i.v.

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