Reactions of Aluminum Oxide Cluster Cations with Ethane: A Mass-Spectrometric and Vibrational Spectroscopy Study.

The pathways for the reactions of aluminum oxide cluster ions with ethane have been measured. For selected ions (AlO, AlO , AlO , AlO ) the structure of the collisionally-stabilized reaction intermediates were explored by measuring the photodissociation vibrational spectra from 2600 cm-3100 cm. Density functional theory was used to calculate features of the potential energy surfaces for the reactions and the vibrational spectra of intermediates.

Rapid Adaptation and Interspecific Introgression in the North American Crop Pest Helicoverpa zea.

Insect crop pests threaten global food security. This threat is amplified through the spread of nonnative species and through adaptation of native pests to control measures. Adaptations such as pesticide resistance can result from selection on variation within a population, or through gene flow from another population.

Pilot Feasibility Study: 18 F-DPA-714 PET/CT Macrophage Imaging in Triple-Negative Breast Cancers (EITHICS).

Abstract: Tumor-associated macrophages are targets of interest in triple-negative breast cancer (TNBC). The translocator protein 18 kDa (TSPO) is a sensitive marker for macrophages and holds potential relevance in TNBC stratification. This pilot prospective study (EITHICS, NCT04320030) aimed to assess the potential of TSPO PET/CT imaging using 18 F-DPA-714 in primary TNBC, compared with immunohistochemistry, autoradiography, and TSPO polymorphism.

How the nature and charge of metal cations affect vibrations in acetone solvent molecules.

Vibrational spectra of a series of gas-phase metal 1+ and 2+ ions solvated by acetone molecules are collected to investigate how the metal charge, number of solvent molecules and nature of the metal affect the acetone. The spectra of Cu(Ace)(N), Cu(Ace), and M(Ace), where M = Co, Ni, Cu, and Zn are measured photodissociation by monitoring fragment ion signal as a function of IR wavenumber. The spectra show a red shift of the CO stretch and a blue shift of the C-C antisymmetric stretch.

Probing adsorption of methane onto vanadium cluster cations via vibrational spectroscopy.

Photofragment spectroscopy is used to measure the vibrational spectra of V2+(CH4)n (n = 1-4), V3+(CH4)n (n = 1-3), and Vx+(CH4) (x = 4-8) in the C-H stretching region (2550-3100 cm-1). Spectra are measured by monitoring loss of CH4. The experimental spectra are compared to simulations at the B3LYP+D3/6-311++G(3df,3pd) level of theory to identify the geometry of the ions.

Al Activates Acetone to Form Pinacolate.

The interaction between aluminum cations and acetone is studied in the gas phase via photodissociation vibrational spectroscopy from 1100 to 2000 cm. Spectra of Al(acetone)(N) and ions with the stoichiometry of Al(acetone) ( = 2-5) were measured. The experimental results are compared to DFT calculated vibrational spectra to determine the structures of the complexes.

Horn fly transcriptome data of ten populations from the southern United States with varying degrees and molecular mechanisms of pesticide resistance.

(Linnaeus, 1758: Diptera: Muscidae), the horn fly, is an external parasite of penned and pastured livestock that causes a major economic impact on cattle production worldwide. Pesticides such as synthetic pyrethroids and organophosphates are routinely used to control horn flies; however, resistance to these chemicals has become a concern in several countries. To further elucidate the molecular mechanisms of resistance in horn fly populations, we sequenced the transcriptomes of ten populations of horn flies from the southern US possessing varying degrees of pesticide resistance levels to pyrethroids, organophosphates, and endosulfans.

Vibrational Spectroscopy and Structural Analysis of V(CH) Clusters ( = 1-4).

The vibrational structure and binding motifs of vanadium cation-ethane clusters, V(CH), for = 1-4 are probed using infrared photodissociation spectroscopy in the C-H stretching region (2550-3100 cm). Comparison of spectra to scaled harmonic frequency spectra obtained using density functional theory suggests that ethane exhibits two primary binding motifs when interacting with the vanadium cation: an end-on η configuration and a side-on configuration. Determining the denticity of the side on isomer is complicated by the rotational motion of ethane, implying that structural analysis based solely on Born-Oppenheimer potential energy surface minimizations is insufficient and that a more sophisticated vibrationally adiabatic approach is necessary to interpret spectra.

Novel cannulation strategy with a bidirectional cannula for distal limb perfusion during peripheral veno-arterial extracorporeal life support: A preliminary, single-centre study.

Introduction: Limb ischemia is a severe complication of peripheral veno-arterial extracorporeal life support (V-A ECLS). Several techniques have been developed to prevent this, but it remains a major and frequent adverse event (incidence: 10-30%). In 2019, a new cannula with bidirectional flow (retrograde towards the heart and antegrade towards the distal limb) has been introduced.

Comparison of Hormone-Sensitive Oligorecurrent Prostate Cancer Patients Based on Routine Use of Choline and/or PSMA PET/CT to Guide Metastasis-Directed Therapy.

Background: In hormone-sensitive oligorecurrent prostate cancer (PC), the literature showed [68Ga]Ga-PSMA (PSMA) and [18F]F-choline (FCH) PET/CT can successfully guide metastasis-directed therapies (MDT). This observational retrospective study aimed to explore, in routine use, the impact of FCH or PSMA PET/CT in guiding MDT for hormone-sensitive oligometastatic PC at different recurrences.

Methods: In 2017-2020, patients initially treated with radical prostatectomy but, in biochemical recurrence (with PSA ≤ 2 ng/mL), diagnosed as oligometastatic based on FCH or PSMA PET/CT, were identified.

Photofragment imaging differentiates between one- and two-photon dissociation pathways in MgI.

The bond strength and photodissociation dynamics of MgI are determined by a combination of theory, photodissociation spectroscopy, and photofragment velocity map imaging. From 17 000 to 21 500 cm, the photodissociation spectrum of MgI is broad and unstructured; photofragment images in this region show perpendicular anisotropy, which is consistent with absorption to the repulsive wall of the (1) Ω = 1 or (2) Ω = 1 states followed by direct dissociation to ground state products Mg (S) + I (P). Analysis of photofragment images taken at photon energies near the threshold gives a bond dissociation energy D(Mg-I) = 203.

Characterization of triatomine bloodmeal sources using direct Sanger sequencing and amplicon deep sequencing methods.

Knowledge of host associations of blood-feeding vectors may afford insights into managing disease systems and protecting public health. However, the ability of methods to distinguish bloodmeal sources varies widely. We used two methods-Sanger sequencing and amplicon deep sequencing-to target a 228 bp region of the vertebrate Cytochrome b gene and determine hosts fed upon by triatomines (n = 115) collected primarily in Texas, USA.

Duplex Analysis of Cannulated Vessels in Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation.

Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) cannulas have major repercussions on vascular hemodynamics that can potentially lead to limb ischemia. Duplex ultrasound enables the non-invasive analysis of vascular hemodynamics. This study aims to describe the duplex parameters of the femoral vessels during V-A ECMO support, investigate differences between cannulated and non-cannulated vessels, and analyze the variations in the case of limb ischemia and intra-aortic balloon pumps (IABPs).

A new strategy for using historical imbalanced yield data to conduct genome-wide association studies and develop genomic prediction models for wheat breeding.

Unlabelled: Using imbalanced historical yield data to predict performance and select new lines is an arduous breeding task. Genome-wide association studies (GWAS) and high throughput genotyping based on sequencing techniques can increase prediction accuracy. An association mapping panel of 227 Texas elite (TXE) wheat breeding lines was used for GWAS and a training population to develop prediction models for grain yield selection.

Cost Effectiveness of Endovascular Revascularisation vs. Exercise Therapy for Intermittent Claudication Due to Iliac Artery Obstruction.

Objective: To compare cost effectiveness of endovascular revascularisation (ER) and supervised exercise therapy (SET) as primary treatment for patients with intermittent claudication (IC) due to iliac artery obstruction.

Methods: Cost utility analysis from a restricted societal perspective and time horizon of 12 months. Patients were included in a multicentre randomised controlled trial (SUPER study, NCT01385774, NTR2648) which compared effectiveness of ER and SET.

Genome-wide QTL mapping of yield and agronomic traits in two widely adapted winter wheat cultivars from multiple mega-environments.

Quantitative trait loci (QTL) analysis could help to identify suitable molecular markers for marker-assisted breeding (MAB). A mapping population of 124 Frecombinant inbred lines derived from the cross 'TAM 112'/'TAM 111' was grown under 28 diverse environments and evaluated for grain yield, test weight, heading date, and plant height. The objective of this study was to detect QTL conferring grain yield and agronomic traits from multiple mega-environments.

Genetic and genomic architecture in eight strains of the laboratory opossum Monodelphis domestica.

The gray short-tailed opossum (Monodelphis domestica) is an established laboratory-bred marsupial model for biomedical research. It is a critical species for comparative genomics research, providing the pivotal phylogenetic outgroup for studies of derived vs ancestral states of genomic/epigenomic characteristics for eutherian mammal lineages. To characterize the current genetic profile of this laboratory marsupial, we examined 79 individuals from eight established laboratory strains.

Case Report: Paucisymptomatic College-Age Population as a Reservoir for Potentially Neutralization-Resistant Severe Acute Respiratory Syndrome Coronavirus 2 Variants.

To better understand the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant lineage distribution in a college campus population, we carried out viral genome surveillance over a 7-week period from January to March 2021. Among the sequences were three novel viral variants: BV-1 with a B.1.

Bonding, Thermodynamics, and Dissociation Dynamics of NiO and NiS Determined by Photofragment Imaging and Theory.

We use photofragment ion imaging and calculations to determine the bond strength and photodissociation dynamics of the nickel oxide (NiO) and nickel sulfide (NiS) cations. NiO photodissociates broadly from 20350 to 32000 cm, forming ground state products Ni(D) + O(P) below ∼29000 cm. Above this energy, Ni(F) + O(P) products become accessible and dominate over the ground state channel.

Structures of M(CH) (M = Ti, V) Based on Vibrational Spectroscopy and Density Functional Theory.

Photofragment spectroscopy is used to measure the vibrational spectra of M(CH)(Ar) and M(CH) (M = Ti, V; = 1-4) in the C-H stretching region (2550-3100 cm). Spectra were measured by monitoring the loss of Ar from M(CH)(Ar) and loss of CH from the larger clusters. The experimental spectra are then compared to simulations done at the B3LYP/6-311++G(3df,3pd) level of theory to identify the structures of the ions.

Raw pacific biosciences and illumina sequencing reads and assembled genome data for the cattle ticks and .

Ticks from the genus have enormous global economic impact as ectoparasites of cattle. and are known to harbor infectious pathogens such as , and . Having reference quality genomes of these ticks would advance research to identify druggable targets for chemical entities with acaricidal activity and refine anti-tick vaccine approaches.

RNA-seq analysis reveals different drought tolerance mechanisms in two broadly adapted wheat cultivars 'TAM 111' and 'TAM 112'.

Wheat cultivars 'TAM 111' and 'TAM 112' have been dominantly grown in the Southern U.S. Great Plains for many years due to their high yield and drought tolerance.